Protein Alignment TBPH and hnrnpdl

DIOPT Version :10

• Sequence 1: NP_477400.1
• Gene: TBPH / 37781
• FlyBaseID: FBgn0025790
• Length: 531
• Species: Drosophila melanogaster
• Sequence 2: NP_001011015.1
• Gene: hnrnpdl / 496424
• XenbaseID: XB-GENE-495016
• Length: 297
• Species: Xenopus tropicalis
• Alignment Length: 271
• Identity: 80/271 - (29%)
• Similarity: 128/271 - (47%)
• Gaps: 30/271 - (11%)

  Fly   109 LIVLGLPWKTTEESLREYFETYGEVLMAQIKKDTKSGQSKGFGFVRFGSYDAQMRVL-TNRHLID 172
            :.:.||.|.|:::.|.||...:|||:...||.|..:|:|:|||||.|....:..:|| |..|.:|
 Frog    28 MFIGGLSWDTSKKDLTEYLSRFGEVVDCTIKTDPVTGRSRGFGFVLFKDAVSVDKVLETKEHKLD 92

  Fly   173 GRWCEVKVPNSKGM-GHQVPCKVFVGRCTEDINSDDLREYFSKFGEVTDVFIP-----RPFRAFS 231
            |:..:.|  .:|.: |.:.|.|||||..:.:...:.:::||..|||:.::.:|     ...|.|.
 Frog    93 GKLIDPK--RAKALKGKEPPKKVFVGGLSPETTEEQIKQYFGGFGEIENIELPMDTKTNERRGFC 155

  Fly   232 FVTFL-DPDVAQSLCGEDHIIKGVSVHVSNAAPKAEQNRNQQVQSYNYNSAN------------- 282
            |||:. :..|.:.|....|.|......:..|.||....:.||.|......|.
 Frog   156 FVTYTGEEPVKKLLESRFHQIGTGKCEIKVAQPKEVYRQQQQKQQKGGRGAATGRGGARGRGRGQ 220

  Fly   283 --SFGMHSYHPQGNHMNPGRNGHHRGNNQHNAHGGENAIVPNNHNIGTAGYGMGGNNYGG-NSGG 344
              :.|..:|:.| |:.:.|.||.:.....:|::.|.:.   :.:|.|:.||..|..:|.| .|..
 Frog   221 GWNQGYSNYYDQ-NYGSYGNNGSYADQGYNNSYSGYDY---SGYNYGSYGYNQGYTDYSGQQSTY 281

  Fly   345 GYHNNGGNHSS 355
            |....||||.:
 Frog   282 GKARGGGNHQN 292

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
TBPH	NP_477400.1	TDP43_N	3..78	CDD:465833
		RRM1_TDP43	108..181	CDD:409760	28/72 (39%)
		RRM2_TDP43	192..261	CDD:409761	20/74 (27%)
hnrnpdl	NP_001011015.1	Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite	1..21
		RRM1_hnRPDL	27..102	CDD:410152	28/75 (37%)
		RRM2_hnRPDL	112..186	CDD:409998	20/73 (27%)
		Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite	192..224		4/31 (13%)
		Trnau1ap	223..>272	CDD:465438	14/52 (27%)