DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment TBPH and mod

DIOPT Version :9

Sequence 1:	NP_001163280.1	Gene:	TBPH / 37781	FlyBaseID:	FBgn0025790	Length:	531	Species:	Drosophila melanogaster
Sequence 2:	NP_001247401.1	Gene:	mod / 43764	FlyBaseID:	FBgn0002780	Length:	542	Species:	Drosophila melanogaster

Alignment Length:	291	Identity:	62/291 - (21%)
Similarity:	105/291 - (36%)	Gaps:	74/291 - (25%)

- Green bases have known domain annotations that are detailed below.

  Fly     2 DFVQVSEEEGDEPIELP------------AEED--------GTLLLSTLQAQ--FPGSCGLKYRN 44
            |.|..|:::.:.|:|.|            :||:        |.:.|.|.:.|  |..:...:|.:
  Fly   124 DEVDESDDDEEAPVEKPVSKKSEKANSEKSEENRGIPKVKVGKIPLGTPKNQIVFVTNLPNEYLH 188

  Fly    45 LDTKAV-----------RGVRSNEGRLFPPSVESGWGEYAYFCVFPK-----------ENKRKSD 87
            .|..|:           |....|..:....:.::..|..|.....||           ...|..:
  Fly   189 KDLVALFAKFGRLSALQRFTNLNGNKSVLIAFDTSTGAEAVLQAKPKALTLGDNVLSVSQPRNKE 253

  Fly    88 DNLENSTAKTKRIETRLRCTDLIVLGL--PWKTTEESLREYFETYGEVLMAQIKKDTKSGQSKGF 150
            :|.|.:                :|:||  | ..|::.|:.:||....|....|    .|.:....
  Fly   254 ENNERT----------------VVVGLIGP-NITKDDLKTFFEKVAPVEAVTI----SSNRLMPR 297

  Fly   151 GFVRFGSYDAQMRVLTNRHLID--GRWCEVKVPNSKGMGHQVPCKVF---VGRCTEDINSDDLRE 210
            .|||..|.|...:.| ..|..:  .|:..|:..:.:.:.......:.   ||: .|..:||.|.:
  Fly   298 AFVRLASVDDIPKAL-KLHSTELFSRFITVRRISQESISRTSELTLVVENVGK-HESYSSDALEK 360

  Fly   211 YFSKFGEVTDVFIPRPFRAFSFVTFLDPDVA 241
            .|.|||:|.::.:.......:||||...|.|
  Fly   361 IFKKFGDVEEIDVVCSKAVLAFVTFKQSDAA 391

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
TBPH	NP_001163280.1	RRM1_TDP43	108..184	CDD:240767	20/79 (25%)
TBPH	NP_001163280.1	RRM2_TDP43	192..261	CDD:240768	17/53 (32%)
mod	NP_001247401.1	RRM_SF	177..244	CDD:302621	10/66 (15%)
		RRM_SF	260..327	CDD:240668	19/72 (26%)
		RRM_SF	342..411	CDD:240668	17/51 (33%)
		RRM_SF	422..>465	CDD:302621
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	1	0.930	-	-		C45439638
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	0	0.000	Not matched by this tool.
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
	1	0.930