Protein Alignment TBPH and rbm34

DIOPT Version :10

• Sequence 1: NP_477400.1
• Gene: TBPH / 37781
• FlyBaseID: FBgn0025790
• Length: 531
• Species: Drosophila melanogaster
• Sequence 2: NP_001002382.1
• Gene: rbm34 / 436655
• ZFINID: ZDB-GENE-040718-77
• Length: 411
• Species: Danio rerio
• Alignment Length: 280
• Identity: 59/280 - (21%)
• Similarity: 101/280 - (36%)
• Gaps: 77/280 - (27%)

  Fly     8 EEEGDEP------IELPAEEDGTLLLSTLQAQFPGSC----------------GLKYRNL---DT 47
            |:|.:.|      ::..|||...:..:......|.||                .:::|::   |.
Zfish   124 EDEEERPTKHKKTVKFNAEERLKMKRTVFVGNLPSSCKKKDLLSVFKKSGVIESVRFRSVIREDP 188

  Fly    48 KAVRGVRSNEGRLFPPSVESGWGEYAYFCVFPKENKRKSDD--------------NLENSTAKTK 98
            ...|.|.:.:.::.|.  :.....|..|    ||.:..:|.              .::..:..:|
Zfish   189 TMSRKVAAIQRKVHPK--KQNINAYIVF----KEEESATDALKWNGHEIQAGFYIRVDRVSQHSK 247

  Fly    99 RIETRLRCTDLIVLGLPWKTTEESLREYFETYGEVLMAQIKKDTKSGQSKGFGFVRFGSYDAQMR 163
            ....|    .:.|..||:..:|..|:.:|:..|.:...::.:|..||..||||:|.|.|.|:.|.
Zfish   248 HDHKR----SIFVGNLPYDISELPLQNHFQECGNIEAVRLVRDRDSGMGKGFGYVLFESPDSVML 308

  Fly   164 VL-TNRHLIDGRWCEVKVPNSKGMGHQVPCKVFVGRCTE-------------DINSDDLREYFSK 214
            .| .|...:..|...||....|....:.|    .||..|             :..::..|:.|:|
Zfish   309 ALKLNGSTLQQRKIRVKRSVKKEKEKKTP----PGRKAEGQRTGGGLKGPKQEFRNNTGRKNFTK 369

  Fly   215 FGEVTDVFIPR--PFRAFSF 232
                    .||  |.:|.||
Zfish   370 --------NPRNKPTQASSF 381

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
TBPH	NP_477400.1	TDP43_N	3..78	CDD:465833	16/94 (17%)
		RRM1_TDP43	108..181	CDD:409760	24/73 (33%)
		RRM2_TDP43	192..261	CDD:409761	12/56 (21%)
rbm34	NP_001002382.1	RRM1_RBM34	149..240	CDD:409828	13/96 (14%)
		RRM2_RBM34	253..325	CDD:409829	22/71 (31%)