Protein Alignment TBPH and trv

DIOPT Version :10

• Sequence 1: NP_477400.1
• Gene: TBPH / 37781
• FlyBaseID: FBgn0025790
• Length: 531
• Species: Drosophila melanogaster
• Sequence 2: NP_001163754.3
• Gene: trv / 43362
• FlyBaseID: FBgn0085391
• Length: 651
• Species: Drosophila melanogaster
• Alignment Length: 339
• Identity: 70/339 - (20%)
• Similarity: 112/339 - (33%)
• Gaps: 118/339 - (34%)

  Fly    81 ENKRKSDDNLENSTAKTKRIETRLRCTDLIVLGLPWKTTEESLREYFETYGEVLMAQIKKDTKSG 145
            ::...||:.:|......|:..       :.|..|..:...:.|||.|..:||:...::.:|.::.
  Fly   293 QDMEDSDEEMEYMPPLHKQFH-------IFVGDLSSEIETQQLREAFTPFGEISDCRVVRDPQTL 350

  Fly   146 QSKGFGFVRF--------------GSYDAQMRVLTNRHLIDGRWCEVKVPNSK------------ 184
            :|||:|||.|              |.:.....:.||       |...|.|.||
  Fly   351 KSKGYGFVSFIKKSEAESAITAMNGQWLGSRSIRTN-------WATRKPPASKENIKPLTFDEVY 408

  Fly   185 GMGHQVPCKVFVGRCTEDINS-------DDLREYFSKFGEVTDVFIPRPF--RAFSFVTFLDPDV 240
            .......|.|:||    .:||       :.|::.|:.:|.:.::   |.|  :.::||.|...:.
  Fly   409 NQSSPSNCTVYVG----GVNSALTALSEEVLQKTFAPYGAIQEI---RVFKDKGYAFVRFSTKEA 466

  Fly   241 AQSLCGEDHIIKGVSVHVSNAAP--------KAEQNRNQQVQSYNYNSANS------FGMHS--- 288
            |      .|.|.||.....||.|        ..:.|..|.:.:...|||.:      :|:.:
  Fly   467 A------THAIVGVHNTEINAQPVKCSWGKESGDPNNAQTIATQALNSAAAAAAGFPYGVGAAAA 525

  Fly   289 --------------YHPQGNH---------MNPGRNGHHRGNNQHNAHGGENAIVPNNHNIGTAG 330
                          |.|...:         :.|.              ....|.|.|....|..|
  Fly   526 AAAYGQQLAATGCWYSPTPTYPASSATAAAVTPA--------------AASAAAVQNQFLQGIQG 576

  Fly   331 YGMGGNNYGGNSGG 344
            |..|  .|||...|
  Fly   577 YHFG--QYGGYQQG 588

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
TBPH	NP_477400.1	TDP43_N	3..78	CDD:465833
		RRM1_TDP43	108..181	CDD:409760	21/86 (24%)
		RRM2_TDP43	192..261	CDD:409761	19/77 (25%)
trv	NP_001163754.3	RRM2_TIA1_like	313..387	CDD:409789	19/87 (22%)
		RRM3_TIA1_like	416..489	CDD:409790	22/85 (26%)