Protein Alignment TBPH and sqd

DIOPT Version :10

• Sequence 1: NP_477400.1
• Gene: TBPH / 37781
• FlyBaseID: FBgn0025790
• Length: 531
• Species: Drosophila melanogaster
• Sequence 2: NP_731825.1
• Gene: sqd / 41666
• FlyBaseID: FBgn0263396
• Length: 344
• Species: Drosophila melanogaster
• Alignment Length: 336
• Identity: 106/336 - (31%)
• Similarity: 146/336 - (43%)
• Gaps: 68/336 - (20%)

  Fly    86 SDDNLENSTAKTKRIETRLRCTDLIVLGLPWKTTEESLREYFETYGEVLMAQIKKDTKSGQSKGF 150
            |.||  .|.|..:|.:.|    .|.|.||.|:|||:.||::|..|||:....:|.|.::|:|:||
  Fly    41 SSDN--QSAASGQRDDDR----KLFVGGLSWETTEKELRDHFGKYGEIESINVKTDPQTGRSRGF 99

  Fly   151 GFVRFGSYDAQMRV-LTNRHLIDGRWCEVKVPNSKGMGHQVPCKVFVGRCTEDINSDDLREYFSK 214
            .|:.|.:.:|..:| ..:.|:|:.:    ||...|.....  .|:|||..|.:|:.::::.||.:
  Fly   100 AFIVFTNTEAIDKVSAADEHIINSK----KVDPKKAKARH--GKIFVGGLTTEISDEEIKTYFGQ 158

  Fly   215 FGEVTDVFIP-----RPFRAFSFVTFLDPDVAQSLC-GEDHIIKGVSVHVSNAAPKAEQNRNQQV 273
            ||.:.:|.:|     ...:.|.|:||....|...|. .....|.|..|.|..|.||.|   ||.:
  Fly   159 FGNIVEVEMPFDKQKSQRKGFCFITFDSEQVVTDLLKTPKQKIAGKEVDVKRATPKPE---NQMM 220

  Fly   274 QSYNYNSANSFGMHSYHPQGNHMNPGRNGH-HRG--NNQHNAHGGENAIVPNNHNIGTAGYGMGG 335
            .          ||.. .|:|. |..||.|: .||  |||.:..|..     ..:..|..|||.||
  Fly   221 G----------GMRG-GPRGG-MRGGRGGYGGRGGYNNQWDGQGSY-----GGYGGGYGGYGAGG 268

  Fly   336 ----------NNY-----GGNSGGGYHNNGGNHSSGGNTNRQDGGSQYNSRQSNFHGMNQPHNGN 385
                      |.|     |...|||:..||.....|||.....||.:         |...|..|
  Fly   269 YGDYYAGGYYNGYDYGYDGYGYGGGFEGNGYGGGGGGNMGGGRGGPR---------GGGGPKGG- 323

  Fly   386 VGGSNGWMNRG 396
             ||.||...||
  Fly   324 -GGFNGGKQRG 333

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
TBPH	NP_477400.1	TDP43_N	3..78	CDD:465833
		RRM1_TDP43	108..181	CDD:409760	27/73 (37%)
		RRM2_TDP43	192..261	CDD:409761	22/74 (30%)
sqd	NP_731825.1	RRM1_hnRNPA_hnRNPD_like	58..129	CDD:409763	28/74 (38%)
		RRM2_hnRNPD_like	137..211	CDD:240775	22/73 (30%)