Protein Alignment TBPH and hnrnpdl

DIOPT Version :10

• Sequence 1: NP_477400.1
• Gene: TBPH / 37781
• FlyBaseID: FBgn0025790
• Length: 531
• Species: Drosophila melanogaster
• Sequence 2: NP_001315423.1
• Gene: hnrnpdl / 406701
• ZFINID: ZDB-GENE-040426-2717
• Length: 296
• Species: Danio rerio
• Alignment Length: 309
• Identity: 99/309 - (32%)
• Similarity: 140/309 - (45%)
• Gaps: 42/309 - (13%)

  Fly    78 FPKENKRKSDDNLENSTAKTKRIETRLRCTDLIVLGLPWKTTEESLREYFETYGEVLMAQIKKDT 142
            ||:.:|..:..|.|:.             ..:.:.||.|.|:::.|.:|...:||||...||.|.
Zfish    14 FPEGSKINASKNQEDD-------------GKMFIGGLSWDTSKKDLTDYLSRFGEVLDCTIKTDP 65

  Fly   143 KSGQSKGFGFVRFGSYDAQMRVL-TNRHLIDGRWCEVKVPNSKGM-GHQVPCKVFVGRCTEDINS 205
            .:|:|:|||||.|...::..||| ...|.:||:..:.|  .:|.: |.:.|.|||||..:.||..
Zfish    66 LTGRSRGFGFVLFKDAESVDRVLELTEHKLDGKLIDPK--RAKAIKGKEPPKKVFVGGLSPDITE 128

  Fly   206 DDLREYFSKFGEVTDVFIP-----RPFRAFSFVTF-LDPDVAQSLCGEDHIIKGVSVHVSNAAPK 264
            :.|||||..:||:..:.:|     ...|.|.|||| |:..|.:.|....|.|......:..|.||
Zfish   129 EQLREYFGVYGEIESIELPTDTKTNERRGFCFVTFALEEPVQKLLENRYHQIGSGKCEIKVAQPK 193

  Fly   265 AEQNRNQQVQSYNYNSANSFGMHSYHPQGNHMNPGRNGHHRGNNQHNAHGGENAIVPNNHNIGTA 329
             |..|.||.:...:..... |......:|...|.|.|.:: |.|....:|       |.:|.|..
Zfish   194 -EVYRQQQNRDRGFGGGRG-GFRGRGGRGQGFNQGYNNYY-GQNYGGGYG-------NGYNQGYN 248

  Fly   330 GY------GMGGNNYGGNSGGGYHNNGGNHSSGGNTNRQDGGSQYNSRQ 372
            ||      |....|||  .|.||.:..|..||.|..:| |.|:..||.|
Zfish   249 GYSGYDYSGYNYQNYG--YGQGYDDYSGQQSSYGKASR-DSGNHQNSYQ 294

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
TBPH	NP_477400.1	TDP43_N	3..78	CDD:465833	99/309 (32%)
		RRM1_TDP43	108..181	CDD:409760	28/73 (38%)
		RRM2_TDP43	192..261	CDD:409761	26/74 (35%)
hnrnpdl	NP_001315423.1	RRM_SF	31..106	CDD:473069	28/76 (37%)
		RRM2_hnRPDL	116..190	CDD:409998	26/73 (36%)