Protein Alignment TBPH and hnrnpabb

DIOPT Version :10

• Sequence 1: NP_477400.1
• Gene: TBPH / 37781
• FlyBaseID: FBgn0025790
• Length: 531
• Species: Drosophila melanogaster
• Sequence 2: NP_998467.1
• Gene: hnrnpabb / 406594
• ZFINID: ZDB-GENE-040426-2516
• Length: 309
• Species: Danio rerio
• Alignment Length: 332
• Identity: 90/332 - (27%)
• Similarity: 148/332 - (44%)
• Gaps: 53/332 - (15%)

  Fly    78 FPKENKRKSDDNL-------ENSTAKTKRIETRLRCTD----LIVLGLPWKTTEESLREYFETYG 131
            |.:.::..:::||       ||...:..:|:.. :|.:    :.|.||.|.|:::.|::||..:|
Zfish     6 FMETSENGNEENLNGGEAAGENGAGEGLQIDAS-KCEEDAGKMFVGGLSWDTSKKDLKDYFSKFG 69

  Fly   132 EVLMAQIKKDTKSGQSKGFGFVRFGSYDAQMRVLTNR-HLIDGRWCEVKVPNSKGMGHQVPCKVF 195
            ||:...||.|:.:|:|:||||:.|...|:..|||..: |.:|||..:.|  .:..:..:...|:|
Zfish    70 EVMDCTIKMDSNTGRSRGFGFILFKESDSVDRVLQQKEHRLDGRQIDPK--RAMAIKKEPVKKIF 132

  Fly   196 VGRCTEDINSDDLREYFSKFGEVTDVFIP-----RPFRAFSFVTFLDPDVAQSLCGED-HIIKGV 254
            ||....:...:.:||||..|||:..:.:|     ...|.|.|:||.:....:.:..:. |.:.|.
Zfish   133 VGGLNPETTEEKIREYFGSFGEIETIELPTDPKTSKRRGFVFITFKEEFAVKKILEKKYHNVCGS 197

  Fly   255 SVHVSNAAPKAEQNRNQQVQSYNYNSANSFGMHSYHPQGNHMNPGRNGHHRGNNQHN-AHGGENA 318
            ...:..|.|| |..:.||..:    ....||.......|    ||::.:...||..| .:||:
Zfish   198 KCEIKIAQPK-EIYQQQQFGA----RGGGFGGRGRGRGG----PGQSWNQGYNNYWNQGYGGQ-- 251

  Fly   319 IVPNNHNIGTAGYGMGG-NNYGGNSG-GGYHNNGGNHSSGGNTNRQDGGSQYNSRQSNFHGMNQP 381
                       |||.|| ..|||..| |.|..:.|.:..|       .|..|..:.:..:|....
Zfish   252 -----------GYGYGGQQGYGGYGGYGNYDYSSGYYGYG-------SGYDYTDQGAASYGKTPR 298

  Fly   382 HNGNVGG 388
            ..|:..|
Zfish   299 RGGHQSG 305

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
TBPH	NP_477400.1	TDP43_N	3..78	CDD:465833	90/332 (27%)
		RRM1_TDP43	108..181	CDD:409760	30/77 (39%)
		RRM2_TDP43	192..261	CDD:409761	19/74 (26%)
hnrnpabb	NP_998467.1	CBFNT	2..45	CDD:311868	7/39 (18%)
		RRM1_hnRNPAB	41..120	CDD:410151	30/80 (38%)
		RRM_SF	125..204	CDD:473069	19/78 (24%)