Protein Alignment TBPH and lark

DIOPT Version :10

• Sequence 1: NP_477400.1
• Gene: TBPH / 37781
• FlyBaseID: FBgn0025790
• Length: 531
• Species: Drosophila melanogaster
• Sequence 2: NP_523957.1
• Gene: lark / 38811
• FlyBaseID: FBgn0011640
• Length: 352
• Species: Drosophila melanogaster
• Alignment Length: 271
• Identity: 61/271 - (22%)
• Similarity: 97/271 - (35%)
• Gaps: 75/271 - (27%)

  Fly   109 LIVLGLPWKTTEESLREYFETYGEVLMAQIKKDTKSGQSKGFGFVRFGS----YDAQMRVLTNRH 169
            |.:..|..||....||..||.||.|:...:.|:        :|||...:    .||...:  |.:
  Fly     9 LFIGNLDEKTQATELRALFEKYGTVVECDVVKN--------YGFVHMETEQQGRDAIQNL--NGY 63

  Fly   170 LIDGRWCEVKVPNSKGMGHQVPCKVFVGRCTEDINSDDLREYFSKFGEVTDVFIPRPFRAFSFVT 234
            .::....:|:...|:...:....|:|||..|:...:.::||.|.|:|.|.:..|   .|.:.||
  Fly    64 TLNEFAIKVEAAKSRRAPNTPTTKIFVGNLTDKTRAPEVRELFQKYGTVVECDI---VRNYGFV- 124

  Fly   235 FLD-----PDVAQSLCGEDHIIKG--VSVHVSNAAPKAEQNRNQQVQSYNYNSANSFGMHSYHPQ 292
            .||     .|..:.|.|  .::.|  :.|.||.:..:.:.......|.|..
  Fly   125 HLDCVGDVQDAIKELNG--RVVDGQPLKVQVSTSRVRPKPGMGDPEQCYRC-------------- 173

  Fly   293 GNHMNPGRNGHHRGNNQHNAHGGENAIVPNNHNIGTAGYGMGGNNYGGNSGGGYHNNGGNHSSGG 357
                  ||:||.            :...|..:               |::||| .......|:||
  Fly   174 ------GRSGHW------------SKECPRLY---------------GSAGGG-REPPSPLSAGG 204

  Fly   358 NTNRQDGGSQY 368
            ..:|..|...|
  Fly   205 YRDRMYGRDPY 215

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
TBPH	NP_477400.1	TDP43_N	3..78	CDD:465833
		RRM1_TDP43	108..181	CDD:409760	19/75 (25%)
		RRM2_TDP43	192..261	CDD:409761	24/75 (32%)
lark	NP_523957.1	RRM1_2_CoAA_like	8..73	CDD:409779	18/73 (25%)
		RRM1_2_CoAA_like	87..152	CDD:409779	21/70 (30%)
		hnRNP-R-Q	<88..>258	CDD:273732	40/182 (22%)