DRSC/TRiP Functional Genomics Resources

powered by:
logo

back to: DIOPT - Ortholog Prediction Tool / DIOPT for Diseases and Traits


Protein Alignment TBPH and CG1316

DIOPT Version :10

Sequence 1:NP_477400.1 Gene:TBPH / 37781 FlyBaseID:FBgn0025790 Length:531 Species:Drosophila melanogaster
Sequence 2:NP_647887.1 Gene:CG1316 / 38526 FlyBaseID:FBgn0035526 Length:470 Species:Drosophila melanogaster


Alignment Length:399 Identity:83/399 - (20%)
Similarity:122/399 - (30%) Gaps:170/399 - (42%)


- Green bases have known domain annotations that are detailed below.


  Fly   119 TEESLREYFETYGEVLMAQIKKDTKSGQSKGFGFVRF------------------GSYDAQMRVL 165
            |||..||.|..|||:....:.||..:.::||..:|:|                  |..|..::||
  Fly    39 TEEDFREAFSPYGEIEDIWVVKDKHTQENKGIAYVKFSKTSDAAKAQEEMNGKTIGKMDRTLKVL 103

  Fly   166 TNRHLIDGRWCEVKVPNSKGMGHQVP-CKVFV---GRCTEDINSDDLREYFSKFGEVTDVFI--- 223
            ...:...|        ::|....|.. .::|:   ...||    :|:||.||::|:|..|.|   
  Fly   104 VAANRNQG--------SNKSENEQEKYVRLFIVIPKTATE----EDIREEFSQWGDVESVTIVKE 156

  Fly   224 -----PRPFRAFSFVTFLDPDVAQSLCGEDHIIKGVSVHVSNAAPKAEQNRNQQVQSYNYNSANS 283
                 |:.|....|..|....||...|...:  |.|.     |.||. ..|.|:.|.        
  Fly   157 KNNGNPKGFGYVRFTKFYYAAVAFENCSAKY--KAVF-----AEPKG-STRTQRDQY-------- 205

  Fly   284 FGMHSYHPQGNHMNPGRNGHHRGNNQHNAHGGENAIVPNNHNIGTAGYGMGGNNYGGNSGGGYHN 348
                           ||                    |:..|...:..|.|.:|:          
  Fly   206 ---------------GR--------------------PSEDNPLYSSSGRGNSNF---------- 225

  Fly   349 NGGNHSSGGNTNRQDGGSQYNSRQSNFHGMNQPHNGNVGGSNGWMNRGHLDMPNLQALGINSQGS 413
            |||..||||.     |.:.||                    |.|                     
  Fly   226 NGGGSSSGGG-----GSNSYN--------------------NDW--------------------- 244

  Fly   414 SSSNQGQNMSNQSMLNLNSLPI-NPALVAAALNQWSLVGNQLQNQNQDQ--------QGGNFLSW 469
               |..||....:.|.:.::|: .|:.:..         |.....||||        .|.::...
  Fly   245 ---NVSQNNDMAAFLRMQNVPVAQPSCLEV---------NVSNCVNQDQLWRLFDIIPGLDYCQI 297

  Fly   470 MAQNGGHNN 478
            |.::|...|
  Fly   298 MREHGPRTN 306

Known Domains:


Indicated by green bases in alignment.

GeneSequenceDomainRegion External IDIdentity
TBPHNP_477400.1 TDP43_N 3..78 CDD:465833
RRM1_TDP43 108..181 CDD:409760 20/79 (25%)
RRM2_TDP43 192..261 CDD:409761 21/79 (27%)
CG1316NP_647887.1 RRM1_RBM45 25..105 CDD:409801 19/65 (29%)
RRM_SF 122..195 CDD:473069 22/83 (27%)
RRM3_RBM45 267..339 CDD:409803 9/49 (18%)
RRM4_RBM45 383..449 CDD:409804
Blue background indicates that the domain is not in the aligned region.

Return to query results.
Submit another query.