Protein Alignment TBPH and tra2

DIOPT Version :10

• Sequence 1: NP_477400.1
• Gene: TBPH / 37781
• FlyBaseID: FBgn0025790
• Length: 531
• Species: Drosophila melanogaster
• Sequence 2: NP_476764.1
• Gene: tra2 / 36619
• FlyBaseID: FBgn0003742
• Length: 264
• Species: Drosophila melanogaster
• Alignment Length: 274
• Identity: 55/274 - (20%)
• Similarity: 97/274 - (35%)
• Gaps: 73/274 - (26%)

  Fly    38 CGLKYRNLDTKAVRGVRSNEGRLFPPSVESGWGEYAYFCVFPKENKRKSDDNLENSTAKTKRIET 102
            ||.: |:..:.:.|..||......||..             |:....:|..:.|. ..|::....
  Fly    45 CGSR-RHQRSSSRRRSRSRSSSESPPPE-------------PRHRSGRSSRDRER-MHKSREHPQ 94

  Fly   103 RLRCTDLIVLGLPWKTTEESLREYFETYGEVLMAQIKKDTKSGQSKGFGFVRFGSY-DAQMRVLT 166
            ..||  :.|.||...|::..:||.|..||.:...|:..|.::.:|:||.|:.|... ||:....:
  Fly    95 ASRC--IGVFGLNTNTSQHKVRELFNKYGPIERIQMVIDAQTQRSRGFCFIYFEKLSDARAAKDS 157

  Fly   167 NRHL-IDGRWCEVKVPNSKGMGHQVPCK-VFVGRCTEDINSDDLREYFSKFGEVTDVFIPRPFRA 229
            ...: :|||  .::|..|.......|.. |::||              ...|:....|.||
  Fly   158 CSGIEVDGR--RIRVDFSITQRAHTPTPGVYLGR--------------QPRGKAPRSFSPR---- 202

  Fly   230 FSFVTFLDPDVAQSLCGEDHIIKGVSVHVSNAAPKAEQNRNQQVQSYNYNSANSFGMHSYHPQGN 294
                                  :|..|:...:|...:..|::    |:|.       :..:.:..
  Fly   203 ----------------------RGRRVYHDRSASPYDNYRDR----YDYR-------NDRYDRNL 234

  Fly   295 HMNPGRNGHHRGNN 308
            ..:|.||.:.|..:
  Fly   235 RRSPSRNRYTRNRS 248

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
TBPH	NP_477400.1	TDP43_N	3..78	CDD:465833	8/39 (21%)
		RRM1_TDP43	108..181	CDD:409760	21/74 (28%)
		RRM2_TDP43	192..261	CDD:409761	9/69 (13%)
tra2	NP_476764.1	RRM_TRA2	96..175	CDD:409798	25/82 (30%)