Protein Alignment TBPH and rbm7

DIOPT Version :10

• Sequence 1: NP_477400.1
• Gene: TBPH / 37781
• FlyBaseID: FBgn0025790
• Length: 531
• Species: Drosophila melanogaster
• Sequence 2: NP_956219.1
• Gene: rbm7 / 334784
• ZFINID: ZDB-GENE-030131-6724
• Length: 252
• Species: Danio rerio
• Alignment Length: 303
• Identity: 70/303 - (23%)
• Similarity: 103/303 - (33%)
• Gaps: 100/303 - (33%)

  Fly   109 LIVLGLPWKTTEESLREYFETYGEVLMAQIKKDTKSGQSKGFGFVRFGSYDAQMRV---LTNRHL 170
            |.|..|..:.|||.:.|.|...|.::..:|.|:.: |:||.|.||.| .::..:..   |.|...
Zfish    11 LFVGNLDPQVTEEVIFELFLQAGPLIKVKIPKNNE-GKSKLFAFVNF-KHEVSVPYALNLLNGIR 73

  Fly   171 IDGRWCEVKVP------NSKGM--------------GHQVPCKVFVGRCTEDINSDDLREYFSKF 215
            :.||...:|..      |.:|.              ||:      .||..|.:.|..
Zfish    74 LHGRQLNIKFKTGSSHINQEGKSPANSQNPSPANTPGHR------GGRTPEQMGSPS-------- 124

  Fly   216 GEVTDVFIP-----RPFRAFSFVTFLDPDVAQSLCGEDHIIKGVSVHVSNAAPKAEQNRNQQVQS 275
                  :.|     |||.:        ||..|.                    :|..|...|||.
Zfish   125 ------YSPPQHMQRPFSS--------PDTLQR--------------------QAMMNNMWQVQM 155

  Fly   276 YNYNS-ANSFGMHSYHPQGNHMNPGRNGH--HRGNNQHNAHGGENAIVPNNHNIGTAGYGMGGNN 337
            ..... :.:|......|:|| .:.|.:||  .|.:.|.|          |||......:|.|.||
Zfish   156 QQLQMLSGTFQQGMQQPRGN-ADGGWSGHRGQRHSPQDN----------NNHQGRDQRHGNGANN 209

  Fly   338 Y-----GGNSGGGYHNNGGNHSSGGNTNRQDGGSQYNSRQSNF 375
            |     .|..|..||:   :..|||:........:.:||:..:
Zfish   210 YERNRRDGQRGDFYHH---DDRSGGHNRNYPPDRRRDSREGRW 249

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
TBPH	NP_477400.1	TDP43_N	3..78	CDD:465833
		RRM1_TDP43	108..181	CDD:409760	23/74 (31%)
		RRM2_TDP43	192..261	CDD:409761	11/73 (15%)
rbm7	NP_956219.1	RRM_RBM7	8..82	CDD:410005	22/72 (31%)
		PABP-1234	<11..195	CDD:130689	53/244 (22%)
		Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite	88..137		12/68 (18%)
		Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite	171..252		26/93 (28%)
		PRK12678	<171..>248	CDD:237171	26/90 (29%)