Protein Alignment TBPH and rbm14a

DIOPT Version :10

• Sequence 1: NP_477400.1
• Gene: TBPH / 37781
• FlyBaseID: FBgn0025790
• Length: 531
• Species: Drosophila melanogaster
• Sequence 2: NP_001108616.1
• Gene: rbm14a / 323721
• ZFINID: ZDB-GENE-050522-496
• Length: 471
• Species: Danio rerio
• Alignment Length: 207
• Identity: 54/207 - (26%)
• Similarity: 81/207 - (39%)
• Gaps: 32/207 - (15%)

  Fly   109 LIVLGLPWKTTEESLREYFETYGEVLMAQIKKDTKSGQSKGFGFVRF---GSYDAQMRVLTNRHL 170
            |.|..|..:||::.|...|..:|||:...:.:.        |.||..   |:.|:.:|.|..|
Zfish     9 LFVGNLDLETTQDDLIALFAPFGEVVHITVLRQ--------FAFVHLQGEGAADSAIRDLNGR-- 63

  Fly   171 IDGRWCEVKVPNSKGMGHQVP---CKVFVGRCTEDINSDDLREYFSKFGEVTDV----FIPRPFR 228
             :.|...:.|..|||.    |   .|||||......:.:||.:.||.:|:|.|.    ..|....
Zfish    64 -EYRGRSLVVEESKGR----PLNSTKVFVGNLCASCSVEDLYDLFSPYGKVLDCDKVKTKPSSLT 123

  Fly   229 AFSFVTFLDPDVAQSLCGEDHIIKGVSVHVSNAAPKAEQNRNQQVQSYNYNSANSFGMHSYHPQG 293
            .::||.....:.|      :..|:|:........|.|.:....| ||.|.....|.|.|.:....
Zfish   124 GYAFVYMEHKEDA------EQAIEGLHGTTFMGRPLAVELSKVQ-QSTNKVPCASCGAHGHFAGE 181

  Fly   294 NHMNPGRNGHHR 305
            ..:|.....||:
Zfish   182 CPINRPPMEHHQ 193

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
TBPH	NP_477400.1	TDP43_N	3..78	CDD:465833
		RRM1_TDP43	108..181	CDD:409760	19/74 (26%)
		RRM2_TDP43	192..261	CDD:409761	18/72 (25%)
rbm14a	NP_001108616.1	RRM_SF	7..75	CDD:473069	20/76 (26%)
		RRM_SF	84..156	CDD:473069	20/77 (26%)