Protein Alignment TBPH and hnrnpa0l

DIOPT Version :10

• Sequence 1: NP_477400.1
• Gene: TBPH / 37781
• FlyBaseID: FBgn0025790
• Length: 531
• Species: Drosophila melanogaster
• Sequence 2: NP_001268650.1
• Gene: hnrnpa0l / 321899
• ZFINID: ZDB-GENE-030131-618
• Length: 302
• Species: Danio rerio
• Alignment Length: 312
• Identity: 94/312 - (30%)
• Similarity: 138/312 - (44%)
• Gaps: 43/312 - (13%)

  Fly   109 LIVLGLPWKTTEESLREYFETYGEVLMAQIKKDTKSGQSKGFGFVRFGSYDAQMRVLTNR-HLID 172
            |.|.||..:||:|.||.:||.||::....:..:....:|:.||||.:.|.:.....::.| |::|
Zfish     8 LFVGGLNVQTTDEGLRAHFEQYGQLTDCVVVMNQPLQRSRCFGFVTYSSTEEADAAMSARPHIVD 72

  Fly   173 GRWCEVK---VPNSKGMGHQVP--CKVFVGRCTEDINSDDLREYFSKFGE------VTDVFIPRP 226
            |...::|   .....|....:.  .|:|||...:||..:.|::|||:||.      :||....:.
Zfish    73 GNNVDLKRAVAREDAGKPEMLAKVKKIFVGGLKDDIEDEHLQDYFSQFGPIEKAQVITDKDTGKK 137

  Fly   227 FRAFSFVTFLDPDVA-QSLCGEDHIIKGVSVHVSNAAPKAEQNRNQQVQSYNYNSANSFGMHSYH 290
             |.|.||.|.|.|.| :::..:.|.|.|..|.|..|..|      |::||.........|
Zfish   138 -RGFGFVYFDDNDSADKAVVMKFHSICGHKVEVKKALTK------QEMQSTGGGRGGRGG----- 190

  Fly   291 PQGNHMNPGRNGHHRGNNQHNAHGGENAIVPNNHNIGTA-GYGMGGNNYGGNSGGGYHN-NG--- 350
             :|.....|..|..|| ..:|.:|.:|....||....:. |||.|   |....||||.| ||
Zfish   191 -RGMGRGSGFGGGGRG-GYYNDYGYQNNGFGNNSGYDSQNGYGGG---YSDQMGGGYGNGNGYSD 250

  Fly   351 -----GNHSSGGNTNRQDGGSQYNSRQSNFHGMNQPHNGNVGGSNGWMNRGH 397
                 |..:||....:...|:..:.|||:   ...|..|..|||.|:...|:
Zfish   251 FGEGYGQQASGYGAMKTGYGNYSSGRQSS---GPYPRGGGGGGSGGYGRGGY 299

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
TBPH	NP_477400.1	TDP43_N	3..78	CDD:465833
		RRM1_TDP43	108..181	CDD:409760	24/75 (32%)
		RRM2_TDP43	192..261	CDD:409761	27/75 (36%)
hnrnpa0l	NP_001268650.1	RRM1_hnRNPA0	4..82	CDD:409764	24/73 (33%)
		RRM_SF	98..177	CDD:473069	29/85 (34%)