Protein Alignment TBPH and hnrnpaba

DIOPT Version :10

• Sequence 1: NP_477400.1
• Gene: TBPH / 37781
• FlyBaseID: FBgn0025790
• Length: 531
• Species: Drosophila melanogaster
• Sequence 2: NP_997752.2
• Gene: hnrnpaba / 321466
• ZFINID: ZDB-GENE-030131-185
• Length: 340
• Species: Danio rerio
• Alignment Length: 291
• Identity: 84/291 - (28%)
• Similarity: 120/291 - (41%)
• Gaps: 45/291 - (15%)

  Fly   109 LIVLGLPWKTTEESLREYFETYGEVLMAQIKKDTKSGQSKGFGFVRFGSYDAQMRVLTNR-HLID 172
            :.|.||.|.|:::.|::||..:|||....||.|..:|:|:||||:.|.......:||..: |.:|
Zfish    71 MFVGGLSWDTSKKDLKDYFSKFGEVTDCTIKMDPNTGRSRGFGFILFKEPSGVDKVLAQKEHRLD 135

  Fly   173 GRWCEVKVPNSKGMGHQVPCKVFVGRCTEDINSDDLREYFSKFGEVTDVFIP-----RPFRAFSF 232
            ||..:.|  .:..|..:...|:|||....:...:.:||||..|||:..:.:|     ...|.|.|
Zfish   136 GRQIDPK--KAMAMKKEPVKKIFVGGLNPETTEERIREYFGAFGEIETIELPMDPKSNKRRGFVF 198

  Fly   233 VTFLDPDVAQSLCGED-HIIKGVS--------VHVSNAAPKAEQNRNQQVQSYNYNSANSFGMHS 288
            :||.:.:..:.:..:. |.:.|..        ..:..|.|| |..:.||
Zfish   199 ITFKEEEAVKKILEKKYHNVSGTKDTSGKEGLCEIKIAQPK-EVYQQQQ---------------- 246

  Fly   289 YHPQGNHMNPGRNGHHRGNNQHNAHGGENAIVPNNHNIGTAGYGMGGNNYGGNSGGGYHNNGGNH 353
               .|.....|..|..||....|.:.|.|    |..|.|....|.||  |||..|.|.:...||:
Zfish   247 ---YGGRFGGGGRGRGRGGQGQNWNQGYN----NYWNQGYGNQGYGG--YGGQQGYGGYGGYGNY 302

  Fly   354 SSGGNTNRQDGGSQYNSRQSNFHGMNQPHNG 384
            ...|......||..||  |.|......|..|
Zfish   303 DYSGGYYGGYGGYDYN--QGNTSYGKTPRRG 331

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
TBPH	NP_477400.1	TDP43_N	3..78	CDD:465833
		RRM1_TDP43	108..181	CDD:409760	28/72 (39%)
		RRM2_TDP43	192..261	CDD:409761	19/82 (23%)
hnrnpaba	NP_997752.2	CBFNT	1..69	CDD:311868
		RRM1_hnRNPAB	65..144	CDD:410151	28/74 (38%)
		RRM2_hnRNPAB	149..228	CDD:409997	19/78 (24%)