DRSC/TRiP Functional Genomics Resources

powered by:
logo

back to: DIOPT - Ortholog Prediction Tool / DIOPT for Diseases and Traits


Protein Alignment TBPH and Spx

DIOPT Version :10

Sequence 1:NP_477400.1 Gene:TBPH / 37781 FlyBaseID:FBgn0025790 Length:531 Species:Drosophila melanogaster
Sequence 2:NP_511058.1 Gene:Spx / 31558 FlyBaseID:FBgn0015818 Length:347 Species:Drosophila melanogaster


Alignment Length:202 Identity:48/202 - (23%)
Similarity:77/202 - (38%) Gaps:36/202 - (17%)


- Green bases have known domain annotations that are detailed below.


  Fly   113 GLPWKTTEESLREYFETYGEVLMAQIKKDTKSGQSKGFGFVRF-GSYDAQMRV-LTNRHLIDGRW 175
            ||..|.:|..|.|.|...|.|:...:.||..:...:|:|||.| ...||...: :.|...:.|:.
  Fly    19 GLDDKVSETLLWELFVQAGPVVNVHMPKDRVTQMHQGYGFVEFLSEEDADYGIKIMNMIKLYGKP 83

  Fly   176 CEVKVPNSKGMGHQ----VPCKVFVGRCTEDINSDDLREYFSKFGEVTDVFIPRPFR-------- 228
            ..|    :|...||    |...:|:|....:::...|.:.||.||.:...  |:..|        
  Fly    84 IRV----NKASAHQKNLDVGANIFIGNLDVEVDEKLLYDTFSAFGVILQT--PKIMRDPETGKSK 142

  Fly   229 AFSFVTF---------LDPDVAQSLCGEDHIIKGVSVHVSNAAPKAEQNRNQQVQSYNYNSANSF 284
            :|:|:.|         :|....|.||..       .:.||.|..|..:.......:....:|.:.
  Fly   143 SFAFINFASFEASDAAMDAMNGQYLCNR-------PISVSYAFKKDHKGERHGSAAERLLAAQNP 200

  Fly   285 GMHSYHP 291
            ..|:..|
  Fly   201 STHADRP 207

Known Domains:


Indicated by green bases in alignment.

GeneSequenceDomainRegion External IDIdentity
TBPHNP_477400.1 TDP43_N 3..78 CDD:465833
RRM1_TDP43 108..181 CDD:409760 21/69 (30%)
RRM2_TDP43 192..261 CDD:409761 18/85 (21%)
SpxNP_511058.1 RRM1_SF3B4 15..88 CDD:409771 21/72 (29%)
RRM2_SF3B4 99..181 CDD:409772 19/90 (21%)
Blue background indicates that the domain is not in the aligned region.

Return to query results.
Submit another query.