Protein Alignment TBPH and Rbm34

DIOPT Version :10

• Sequence 1: NP_477400.1
• Gene: TBPH / 37781
• FlyBaseID: FBgn0025790
• Length: 531
• Species: Drosophila melanogaster
• Sequence 2: NP_001014037.1
• Gene: Rbm34 / 307956
• RGDID: 1310161
• Length: 428
• Species: Rattus norvegicus
• Alignment Length: 245
• Identity: 56/245 - (22%)
• Similarity: 100/245 - (40%)
• Gaps: 65/245 - (26%)

  Fly     1 MDFVQVSEEEGDEPIELP-------AEEDGTLLLSTLQAQFPGSCGLK--------YRNLDTKAV 50
            :|......|:|.:..::|       .:.:.|:.:..|    |.:|..|        |..:::...
  Rat   154 LDVALSLNEDGRQRTKVPLNPEEERLKNERTVFVGNL----PVTCNKKKLKSFFKEYGQVESVRF 214

  Fly    51 RGVRSNEG----------RLFPPSVESGWGEYAYFCVFPKENKRKSDDNLENSTAKTK---RI-- 100
            |.|...||          |.|.|..:|    ...:.||.:|  |.:...|:.:.|:..   ||
  Rat   215 RSVMPAEGTLSKKLAAIKRKFHPDQKS----INAYVVFKEE--RAAAKALQRNGAQIAEGFRIRV 273

  Fly   101 ----ETRLRCTDLIVLG-LPWKTTEESLREYFETYGEVLMAQIKKDTKSGQSKGFGFVRFGSYDA 160
                ||..|....:.:| ||::..|.:|.|:|...|.::..:|.::..:|..:|||:|.|.:.||
  Rat   274 DLASETASRDKRSVFVGNLPYRVDESALEEHFLDCGSIVAVRIVRNPLTGVGRGFGYVLFENTDA 338

  Fly   161 QMRVLTNRHLIDGRWCEVKVPNSKGMGHQVPCKVFVGRCTEDINSDDLRE 210
            .       ||      .:|:.||:.||.::       |....:|.:.|::
  Rat   339 V-------HL------ALKLNNSELMGRKL-------RVMRSVNKEKLKQ 368

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
TBPH	NP_477400.1	TDP43_N	3..78	CDD:465833	17/99 (17%)
		RRM1_TDP43	108..181	CDD:409760	20/73 (27%)
		RRM2_TDP43	192..261	CDD:409761	3/19 (16%)
Rbm34	NP_001014037.1	Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite	1..106
		Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite	127..152
		RRM1_RBM34	183..274	CDD:409828	22/100 (22%)
		RRM2_RBM34	286..358	CDD:409829	25/91 (27%)
		Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite	361..428		2/8 (25%)