Protein Alignment TBPH and Eif3g

DIOPT Version :10

• Sequence 1: NP_477400.1
• Gene: TBPH / 37781
• FlyBaseID: FBgn0025790
• Length: 531
• Species: Drosophila melanogaster
• Sequence 2: NP_001013113.1
• Gene: Eif3g / 298700
• RGDID: 1307191
• Length: 320
• Species: Rattus norvegicus
• Alignment Length: 163
• Identity: 43/163 - (26%)
• Similarity: 66/163 - (40%)
• Gaps: 46/163 - (28%)

  Fly    19 AEEDGTLLLSTLQAQ-FPGSCGLKYRNLDTKAVRGVRSNEGRLFPPSVESG---WGEYAYFCVFP 79
            ||:.|   |||.:.: .||         :.:.|:..::..|:..|||:..|   .||       .
  Rat   183 AEQLG---LSTGEKEKLPG---------ELEPVQAAQNKTGKYVPPSLRDGASRRGE-------S 228

  Fly    80 KENKRKSDDNLENSTAKTKRIETRLRCTDLIVLGLPWKTTEESLREYFETYGEVLMAQIKKDTKS 144
            .:..|::|||            ..:|.|:     |...|.|..|:|.|..:|.:....:.||..:
  Rat   229 MQPNRRADDN------------ATIRVTN-----LSEDTRETDLQELFRPFGSISRIYLAKDKTT 276

  Fly   145 GQSKGFGFVRFGSYDAQMRVLTN------RHLI 171
            ||||||.|:.|...:...|.:..      .|||
  Rat   277 GQSKGFAFISFHRREDAARAIAGVSGFGYDHLI 309

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
TBPH	NP_477400.1	TDP43_N	3..78	CDD:465833	16/62 (26%)
		RRM1_TDP43	108..181	CDD:409760	21/70 (30%)
		RRM2_TDP43	192..261	CDD:409761
Eif3g	NP_001013113.1	Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite	1..60
		eIF3G	62..173	CDD:240597
		Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite	205..233		7/34 (21%)
		RRM_eIF3G_like	240..315	CDD:409842	23/75 (31%)