Protein Alignment TBPH and rbm-39

DIOPT Version :10

• Sequence 1: NP_477400.1
• Gene: TBPH / 37781
• FlyBaseID: FBgn0025790
• Length: 531
• Species: Drosophila melanogaster
• Sequence 2: NP_500025.1
• Gene: rbm-39 / 176922
• WormBaseID: WBGene00021921
• Length: 580
• Species: Caenorhabditis elegans
• Alignment Length: 217
• Identity: 51/217 - (23%)
• Similarity: 86/217 - (39%)
• Gaps: 36/217 - (16%)

  Fly    54 RSNEGRLFPPSVESGWGEYAYFCVFPKENKRK-SDDNLENSTAKTKRIETRLRCTD---LIVLGL 114
            |.:.||..||...           .|...:|. ...|..:|..|..::|......|   |:::.:
 Worm   124 RRSPGRRSPPRSR-----------LPGPERRDVMPFNPRHSPPKNAKLELTAEERDQRTLLIMQI 177

  Fly   115 PWKTTEESLREYFETYGEVLMAQIKKDTKSGQSKGFGFVRFGSYDA-QMRVLTNRHLIDG----- 173
            ...|....|.|:|...|.|...:|..|:::|:|||..:|.|...:: .:.:..|...:.|
 Worm   178 ARDTRPRDLEEFFSAVGAVRDVRIITDSRTGRSKGICYVEFWDEESVPLGLALNGQRLMGAPLQI 242

  Fly   174 -RWCEVK-------VPNSKGM---GHQVPCKVFVGRCTEDINSDDLREYFSKFGEVTDVFIP--- 224
             |.|..:       |.::.|.   |::.|..|.|......|:...:|:.|..||.:..:.:.
 Worm   243 QRTCAERNRAANSSVASTLGFVAPGNKGPTHVLVENLHPKIDEKMIRDIFESFGRIEKIDLEVDS 307

  Fly   225 -RPFRAFSFVTFLDPDVAQSLC 245
             |..|.|:.:||.:.|.||..|
 Worm   308 NRENRGFATITFRNADDAQKSC 329

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
TBPH	NP_477400.1	TDP43_N	3..78	CDD:465833	5/23 (22%)
		RRM1_TDP43	108..181	CDD:409760	20/89 (22%)
		RRM2_TDP43	192..261	CDD:409761	16/58 (28%)
rbm-39	NP_500025.1	SF-CC1	140..515	CDD:273721	45/190 (24%)