Protein Alignment TBPH and rsp-8

DIOPT Version :10

• Sequence 1: NP_477400.1
• Gene: TBPH / 37781
• FlyBaseID: FBgn0025790
• Length: 531
• Species: Drosophila melanogaster
• Sequence 2: NP_001255142.1
• Gene: rsp-8 / 176613
• WormBaseID: WBGene00004705
• Length: 309
• Species: Caenorhabditis elegans
• Alignment Length: 342
• Identity: 73/342 - (21%)
• Similarity: 100/342 - (29%)
• Gaps: 142/342 - (41%)

  Fly   105 RCTDLIVLGLPWKTTEESLREYFETYGEVLMAQIKKDTKSGQSKGFGFVRFGSYDAQMRVLTNRH 169
            :|  |.|..|...|||:.||:.|..:||:....:..|..||.|:||||:.|             :
 Worm    76 KC--LGVFNLSSYTTEKDLRDVFGEFGEINKCDLVYDRPSGNSRGFGFIYF-------------N 125

  Fly   170 LIDGRWCEVKVPNSKGMGHQVPCKVFVGRCTEDINSDDLREYFS--KFGEVTDVFIPRPFRAFSF 232
            ||:    :......|             .|..|::...:|..||  |.|
 Worm   126 LIE----DATAARDK-------------LCNTDLDGHKIRVDFSLTKRG---------------- 157

  Fly   233 VTFLDPDVAQSLCGEDHIIKGVSVHVSNAAPKAEQNRNQQVQSYNYNSANSFGMHSYHPQGNHMN 297
                                                                  ||..| |.:|.
 Worm   158 ------------------------------------------------------HSPTP-GQYMG 167

  Fly   298 PGRNGHHRGNNQHNAHGGENAIVPNNHNIGTAGYGMGGNNYGGNSGGGYHNNGGNHSSGGNTNRQ 362
            ..|.|...|..:....||:..   |:..      ..||:.|||:..||....||:...||..:|.
 Worm   168 DRRGGGSSGGGRFGGGGGDRF---NDRG------SRGGDRYGGDRRGGGGGGGGDRYGGGGGDRY 223

  Fly   363 DGGSQYN---------SRQSNFH----GMNQPHNGNVGGSNGWMNRGHLDMPNLQALG------- 407
             ||.:|.         .|:..|.    |.....:|  ||..|...|.|.|.......|
 Worm   224 -GGDRYGGGGGRRGSPDRRGGFRSGGGGGGYMRSG--GGGGGPDRRDHRDNDRNGGGGGHRPYDP 285

  Fly   408 -----INSQGSSSSNQG 419
                 :.|.||.:|..|
 Worm   286 SFRRRVESYGSGNSGGG 302

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
TBPH	NP_477400.1	TDP43_N	3..78	CDD:465833
		RRM1_TDP43	108..181	CDD:409760	22/72 (31%)
		RRM2_TDP43	192..261	CDD:409761	7/70 (10%)
rsp-8	NP_001255142.1	RRM_TRA2	75..154	CDD:409798	29/109 (27%)