Protein Alignment TBPH and eIF3g1

DIOPT Version :10

• Sequence 1: NP_477400.1
• Gene: TBPH / 37781
• FlyBaseID: FBgn0025790
• Length: 531
• Species: Drosophila melanogaster
• Sequence 2: XP_308202.3
• Gene: eIF3g1 / 1269559
• VectorBaseID: AGAMI1_005021
• Length: 271
• Species: Anopheles gambiae
• Alignment Length: 254
• Identity: 51/254 - (20%)
• Similarity: 89/254 - (35%)
• Gaps: 58/254 - (22%)

  Fly    53 VRSNEGRLFPPS--VESGW---GEYAY---------------------FCVFPKENKRKSDDNLE 91
            |.|:.|.|.|||  :|:|.   .||.|                     .||..:::..|..|:..
Mosquito    15 VESDSGSLPPPSEVIENGQKIVTEYKYNKDDKKVKVVRTYKISRVVVPKCVARRKSLAKFGDSAT 79

  Fly    92 NSTAKTKRIETRLRCTDLIVLGLPWKTTEESLREYFETYGEVLMAQIKKDTKSGQSKGFGF-VRF 155
            :......  :|.:...|:.:..:..|..|:......::...:    :|..|..|:...|.. .:.
Mosquito    80 DRPGPNP--QTTMVSEDVFMQFITNKEEEQKNENALDSMKNI----VKCRTCEGEHWSFHCPYKN 138

  Fly   156 GSYDAQMRVL------TNRHLIDGRWCEVKVPNSKG--------MGHQVPCKVFVGRCTEDINSD 206
            .:||...:..      |......|::....:..|:|        .|......:.:...:|.:...
Mosquito   139 SAYDKPTKPTTAPVPETTSSSKPGKYVPPHMKESQGKPGIGGAMRGRDDTSAIRISNLSEAMTEA 203

  Fly   207 DLREYFSKFGEVTDVFIPRP-----FRAFSFVTFLD-PDVAQSL-----CGEDHIIKGV 254
            ||.|...|||..|.:|:.|.     .:.|::|.|.. .|.|.::     .|.||:|..|
Mosquito   204 DLEELVKKFGPHTKMFLSRDKSTGLCKGFAYVHFRSRRDAATAIEVLNGYGYDHLILSV 262

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
TBPH	NP_477400.1	TDP43_N	3..78	CDD:465833	13/50 (26%)
		RRM1_TDP43	108..181	CDD:409760	11/79 (14%)
		RRM2_TDP43	192..261	CDD:409761	20/74 (27%)
eIF3g1	XP_308202.3	eIF3g	25..138	CDD:463545	19/118 (16%)
		RRM_eIF3G_like	191..265	CDD:409842	20/72 (28%)