DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment Pym and Pym1

DIOPT Version :9

Sequence 1:	NP_726372.1	Gene:	Pym / 37780	FlyBaseID:	FBgn0034918	Length:	207	Species:	Drosophila melanogaster
Sequence 2:	XP_030101251.1	Gene:	Pym1 / 78428	MGIID:	1925678	Length:	243	Species:	Mus musculus

Alignment Length:	210	Identity:	71/210 - (33%)
Similarity:	117/210 - (55%)	Gaps:	39/210 - (18%)

- Green bases have known domain annotations that are detailed below.

  Fly    10 GKFIPATKRPDGTWRKARRVKDGYVPQEEVPLYESKGKQFVAQRQAGVPPGMCPLLAAESKKERE 74
            ||:|.:|:||||||||.||||:|||||||||:||:|..:|...:.. :|||:.|.........|.
Mouse    53 GKYIASTQRPDGTWRKQRRVKEGYVPQEEVPVYENKYVKFFKSKPE-LPPGLSPEATTPVTPSRP 116

  Fly    75 KQERTRAKKQEKESGRQPKAPAPGVLVMPPSTCPPPKVSQQQQQQQQQPSGSRDINSISKTLEDT 139
            :...|...|..|.:.::                   |..::|||:::..:.||.::.:|  |.||
Mouse   117 EGGETGLSKTAKRNLKR-------------------KEKRRQQQEKEAEALSRTLDKVS--LGDT 160

  Fly   140 LKLDAAQE--------VVDP---------AKQLKKLRKKIREIEQIESRIQAGEQKKLDKDQLDK 187
            .::.:|.:        ..||         ||::|.||||:|::|:::.||||||..:..::||:|
Mouse   161 AQIPSALQGPQATPLAASDPSDSAATTEKAKKIKNLRKKLRQVEELQQRIQAGEVSQPSREQLEK 225

  Fly   188 VKKKSEILRQIKDLE 202
            :.::..:..:::|||
Mouse   226 LARRRVLEEELEDLE 240

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
Pym	NP_726372.1	Mago-bind	11..35	CDD:286378	17/23 (74%)
Pym1	XP_030101251.1	Mago-bind	54..78	CDD:370406	17/23 (74%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	1	0.930	-	-		C167849663
Domainoid	1	1.000	72	1.000	Domainoid score	I9326
eggNOG	1	0.900	-	-		E1_KOG4325
Hieranoid	1	1.000	-	-
Homologene	0	0.000	Not matched by this tool.
Inparanoid	1	1.050	118	1.000	Inparanoid score	I4784
Isobase	0	0.000	Not matched by this tool.
OMA	1	1.010	-	-		QHG59719
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	1	1.000	-	-		FOG0004103
OrthoInspector	1	1.000	-	-		oto93981
orthoMCL	1	0.900	-	-		OOG6_105546
Panther	1	1.100	-	-	LDO	PTHR22959
Phylome	1	0.910	-	-
RoundUp	1	1.030	-	avgDist	Average_Evolutionary_Distance	R3921
SonicParanoid	1	1.000	-	-		X3373
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	1	0.960	-	-
	14	13.790