DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment Pym and pym1

DIOPT Version :9

Sequence 1:	NP_726372.1	Gene:	Pym / 37780	FlyBaseID:	FBgn0034918	Length:	207	Species:	Drosophila melanogaster
Sequence 2:	NP_001016274.1	Gene:	pym1 / 549028	XenbaseID:	XB-GENE-943122	Length:	200	Species:	Xenopus tropicalis

Alignment Length:	216	Identity:	68/216 - (31%)
Similarity:	121/216 - (56%)	Gaps:	33/216 - (15%)

- Green bases have known domain annotations that are detailed below.

  Fly     1 MST-YLQSSEGKFIPATKRPDGTWRKARRVKDGYVPQEEVPLYESKGKQFVAQRQAGVPPGMCPL 64
            |:| |:....||:|.||:||||:|||.|:||:|||||||||:||:|..:|...:.: :|||:...
Frog     1 MATPYVTDESGKYIAATQRPDGSWRKQRKVKEGYVPQEEVPVYENKYVKFFKSKPS-LPPGLSET 64

  Fly    65 LAAESKKEREKQ---ERTRAKKQEKESGRQPKAPAPGVLVMPPSTCPPPKVSQQQQQQQQQPSGS 126
            .|:..|.::..:   :.|.:|..::...|:.|.                  .|::.:::|.....
Frog    65 DASTGKTQQPSKPDADTTLSKTAKRNMKRKEKR------------------KQEKGEREQVEDAR 111

  Fly   127 RDINSIS-------KTLEDTLKLDAAQE---VVDPAKQLKKLRKKIREIEQIESRIQAGEQKKLD 181
            :|:..::       |.|....|..:|..   ..:.||::|.||||:|::|:::.:|.:||.|:..
Frog   112 QDLERVNISETPVQKNLTSAHKNGSASSDNPAAERAKKIKNLRKKLRQVEELQQKIDSGEIKEPS 176

  Fly   182 KDQLDKVKKKSEILRQIKDLE 202
            |:||:|:.::..:..:|:|||
Frog   177 KEQLEKLSRRKALEEEIEDLE 197

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
Pym	NP_726372.1	Mago-bind	11..35	CDD:286378	16/23 (70%)
pym1	NP_001016274.1	Disordered. /evidence=ECO:0000256\|SAM:MobiDB-lite	1..30		16/28 (57%)
		Mago-bind	12..36	CDD:370406	16/23 (70%)
		Disordered. /evidence=ECO:0000256\|SAM:MobiDB-lite	52..147		16/113 (14%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	1	1.000	46	1.000	Domainoid score	I11935
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	1	1.000	-	-
Homologene	0	0.000	Not matched by this tool.
Inparanoid	1	1.050	115	1.000	Inparanoid score	I4678
OMA	1	1.010	-	-		QHG59719
OrthoDB	1	1.010	-	-		D1545729at2759
OrthoFinder	1	1.000	-	-		FOG0004103
OrthoInspector	1	1.000	-	-		otm48776
Panther	1	1.100	-	-	O	PTHR22959
Phylome	1	0.910	-	-
RoundUp	1	1.030	-	avgDist	Average_Evolutionary_Distance	R3921
SonicParanoid	1	1.000	-	-		X3373
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	11	11.110