DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment Pym and pym1

DIOPT Version :9

Sequence 1:	NP_726372.1	Gene:	Pym / 37780	FlyBaseID:	FBgn0034918	Length:	207	Species:	Drosophila melanogaster
Sequence 2:	NP_956888.2	Gene:	pym1 / 393566	ZFINID:	ZDB-GENE-040426-1464	Length:	194	Species:	Danio rerio

Alignment Length:	214	Identity:	74/214 - (34%)
Similarity:	120/214 - (56%)	Gaps:	33/214 - (15%)

- Green bases have known domain annotations that are detailed below.

  Fly     1 MST-YLQSSEGKFIPATKRPDGTWRKARRVKDGYVPQEEVPLYESKGKQFVAQRQAGVPPGMCPL 64
            |:| |:....||:|.||:||||:|||.|||:||||||||||:||:|..:|...:.. :|||:|..
Zfish     1 MATPYVTDESGKYIAATQRPDGSWRKPRRVRDGYVPQEEVPVYENKFVKFFKSKPE-LPPGVCVE 64

  Fly    65 LAAESKKE--------REKQERTRAKKQEKESGRQPKAPAPGVLVMPPSTCPPPKVSQQQQQQQQ 121
            ...:::.:        |..:...:.|::.::.|::.| |.| .|...|...|.|:.....||.||
Zfish    65 TPPQTQTQPSDAAGLSRTAKRNMKRKEKRRQQGQETK-PEP-ELQPEPELQPEPEPQGLSQQMQQ 127

  Fly   122 QPSGSRDINSISKTLEDTLKLDAAQ--EVVDPAKQLKKLRKKIREIEQIESRIQAGEQKKLDKDQ 184
                              |:|.|:|  ...|.|::||.||||:|::|:::.|:.:||.|. .::|
Zfish   128 ------------------LELSASQGPGAADSARRLKNLRKKLRQVEELQQRVLSGELKP-SQEQ 173

  Fly   185 LDKVKKKSEILRQIKDLES 203
            |||:.:...:..:::.||:
Zfish   174 LDKLGRAQALREELQQLEA 192

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
Pym	NP_726372.1	Mago-bind	11..35	CDD:286378	17/23 (74%)
pym1	NP_956888.2	Disordered. /evidence=ECO:0000256\|SAM:MobiDB-lite	1..33		18/31 (58%)
		Mago-bind	12..36	CDD:286378	17/23 (74%)
		Disordered. /evidence=ECO:0000256\|SAM:MobiDB-lite	54..140		22/106 (21%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	1	1.000	69	1.000	Domainoid score	I9621
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	1	1.000	-	-
Homologene	0	0.000	Not matched by this tool.
Inparanoid	1	1.050	118	1.000	Inparanoid score	I4780
OMA	1	1.010	-	-		QHG59719
OrthoDB	1	1.010	-	-		D1545729at2759
OrthoFinder	1	1.000	-	-		FOG0004103
OrthoInspector	1	1.000	-	-		oto40466
orthoMCL	1	0.900	-	-		OOG6_105546
Panther	1	1.100	-	-	LDO	PTHR22959
Phylome	1	0.910	-	-
RoundUp	1	1.030	-	avgDist	Average_Evolutionary_Distance	R3921
SonicParanoid	1	1.000	-	-		X3373
SwiftOrtho	1	1.000	-	-
TreeFam	0	0.000	Not matched by this tool.
ZFIN	0	0.000	Not matched by this tool.
	13	13.010