Protein Alignment gbb and INHBE

DIOPT Version :9

• Sequence 1: NP_001286786.1
• Gene: gbb / 37778
• FlyBaseID: FBgn0024234
• Length: 455
• Species: Drosophila melanogaster
• Sequence 2: NP_113667.1
• Gene: INHBE / 83729
• HGNCID: 24029
• Length: 350
• Species: Homo sapiens
• Alignment Length: 372
• Identity: 98/372 - (26%)
• Similarity: 152/372 - (40%)
• Gaps: 78/372 - (20%)

  Fly    92 APKFLLDVYHRITAEEGLSDQDEDDDYERGHRSRRSADLEEDEGEQQKNFITDLDKRAIDESDII 156
            |.:.:||..| :|:...::.........|..|..:...:....||:..:|.|..|..:...|  :
Human    47 AKQQILDGLH-LTSRPRITHPPPQAALTRALRRLQPGSVAPGNGEEVISFATVTDSTSAYSS--L 108

  Fly   157 MTFLNKRHHNVDELRHEHGRRLWFDV-SNVPNDNYLVMAELRIY----QNANEG-KWLTANREFT 215
            :||    |.:.....|.:..|||..| ..:|.     ...|||:    :...:| :.|.|....|
Human   109 LTF----HLSTPRSHHLYHARLWLHVLPTLPG-----TLCLRIFRWGPRRRRQGSRTLLAEHHIT 164

  Fly   216 ITVYAIGTGTLGQHTMEPLSSVNTTGDYVGWLELNVTEGLHEWLVKSKDNHGIYIGAHAVNRPDR 280
                     .||.||: .|.|....|:..|.|:|.:            |...:...:....:|.|
Human   165 ---------NLGWHTL-TLPSSGLRGEKSGVLKLQL------------DCRPLEGNSTVTGQPRR 207

  Fly   281 EVKLDDIGLIHRKVDDEFQPFMIGFFRGPEL-IKATAHSSHHRSKRSASHPRKRKKSVSPNNVPL 344
              .||..|  |:      |||:       || |:|        ::..|...|:|        .|.
Human   208 --LLDTAG--HQ------QPFL-------ELKIRA--------NEPGAGRARRR--------TPT 239

  Fly   345 LEPMESTRSCQMQTLYIDFKDLGWHDWIIAPEGYGAFYCSGEC--NFPLNAHMNATNHAIVQTLV 407
            .||  :|..|..:..|:||::|||.|||:.||||...||||:|  :...:..:.|:.|:.|.:|:
Human   240 CEP--ATPLCCRRDHYVDFQELGWRDWILQPEGYQLNYCSGQCPPHLAGSPGIAASFHSAVFSLL 302

  Fly   408 HLLEPKKVPKPCCAPTRLGALPVLYHLNDENVNLKKYRNMIVKSCGC 454
            ....|......||.||....|.:||..::.||......:|:|::|||
Human   303 KANNPWPASTSCCVPTARRPLSLLYLDHNGNVVKTDVPDMVVEACGC 349

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
gbb	NP_001286786.1	TGFb_propeptide	44..305	CDD:279078	49/218 (22%)
		TGFB	354..455	CDD:214556	38/103 (37%)
INHBE	NP_113667.1	TGF_beta	247..349	CDD:306518	36/101 (36%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_KOG3900
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
User_Submission	0	0.000	Not matched by this tool.
	2	1.810