Protein Alignment gbb and Tgfb2

DIOPT Version :10

• Sequence 1: NP_477340.1
• Gene: gbb / 37778
• FlyBaseID: FBgn0024234
• Length: 455
• Species: Drosophila melanogaster
• Sequence 2: NP_112393.2
• Gene: Tgfb2 / 81809
• RGDID: 70491
• Length: 442
• Species: Rattus norvegicus
• Alignment Length: 316
• Identity: 88/316 - (27%)
• Similarity: 135/316 - (42%)
• Gaps: 75/316 - (23%)

  Fly   180 FDVSNV-PNDNYLVMAELRIYQNANEGKWLTANREFTITVYAI-GTGTLGQHTMEPLSS--VNTT 240
            ||||.: .|.:.||.||.|:::..|....:...|   |.:|.| .:..|...|...:.|  |.|.
  Rat   160 FDVSTMEKNASNLVKAEFRVFRLQNPKARVAEQR---IELYQILKSKDLTSPTQRYIDSKVVKTR 221

  Fly   241 GDYVG-WLELNVTEGLHEWLVKSKDNHGIYIGAHA------------VNRPDREVKLDDIGLIHR 292
            .:  | ||..:||:.:||||.....|.|..|..|.            :....:|::....|:
  Rat   222 AE--GEWLSFDVTDAVHEWLHHKDRNLGFKISLHCPCCTFIPSNNYIIPNKSQELEARFAGI--- 281

  Fly   293 KVDDEFQPFMIGFFRGPELIKATAHSSHHRSKRSASHPRKRKKSVSPNNVPLLEP---MESTRS- 353
               |....:..|   ..:.||:|               ||:....:|:.:.:|.|   :||.:|
  Rat   282 ---DGTSTYASG---DQKTIKST---------------RKKSSGKTPHLLLMLLPSYRLESQQSS 325

  Fly   354 -------------------CQMQTLYIDFK-DLGWHDWIIAPEGYGAFYCSGECNFPLNAHMNAT 398
                               |.::.|||||| |||| .||..|:||.|.:|:|.|.:..::.   |
  Rat   326 RRRKRALDAAYCFRNVQDNCCLRPLYIDFKRDLGW-KWIHEPKGYNANFCAGACPYLWSSD---T 386

  Fly   399 NHAIVQTLVHLLEPKKVPKPCCAPTRLGALPVLYHLNDENVNLKKYRNMIVKSCGC 454
            .|..|.:|.:.:.|:....|||....|..|.:||::.: ...:::..|||||||.|
  Rat   387 QHTKVLSLYNTINPEASASPCCVSQDLEPLTILYYIGN-TPKIEQLSNMIVKSCKC 441

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
gbb	NP_477340.1	TGFb_propeptide	45..305	CDD:459906	36/141 (26%)
		TGF_beta_BMP5_like	353..455	CDD:381639	41/123 (33%)
Tgfb2	NP_112393.2	TGFb_propeptide	21..256	CDD:459906	33/100 (33%)
		TGF_beta_TGFB2	345..441	CDD:381655	39/100 (39%)