Protein Alignment gbb and ndr1

DIOPT Version :10

• Sequence 1: NP_477340.1
• Gene: gbb / 37778
• FlyBaseID: FBgn0024234
• Length: 455
• Species: Drosophila melanogaster
• Sequence 2: NP_571041.1
• Gene: ndr1 / 799352
• ZFINID: ZDB-GENE-990415-256
• Length: 392
• Species: Danio rerio
• Alignment Length: 374
• Identity: 90/374 - (24%)
• Similarity: 135/374 - (36%)
• Gaps: 134/374 - (35%)

  Fly   152 ESDIIMTFLNKRHHNV-DELRHEHGRRLWFDVSNVPNDNYLVMAELRIYQNANEGKWLTANREFT 215
            |||.:::.:.|..|.| |:.      .:.||:|::...:.:..|||||       :......|..
Zfish    83 ESDSVLSLVAKSCHQVGDKF------AVTFDMSSISASDDVQRAELRI-------RLPHLRSELE 134

  Fly   216 ITVYAIGT---------------GTLGQHTMEPLSSVNTTGDYVGWLELNVTEGLHEWL------ 259
            :.:|...|               |||..:   |::|...:    .|...|:|..|..||
Zfish   135 VDIYHASTPECERSPCEEVRVHLGTLNAN---PINSTFRS----SWRIFNITALLKYWLHQSERV 192

  Fly   260 -----------------------------VKSKDN------------HGIYI-------GAHAVN 276
                                         |.||.|            |..|:       |:..|.
Zfish   193 PFEEPTQMPPMAEGHKSVHHPTANRVMMVVYSKQNRAKTSTLIRTAEHSKYVALDRAGGGSEPVP 257

  Fly   277 RPDREVKLDDIGLIHRKVDDEFQPFMIGFFRGPELIKATAHSSHHRSKRSASHPRKRKKSVSPNN 341
            |..|.         :.:.||..:....|...|                  .||....||
Zfish   258 RRHRR---------NHRTDDRVRDAAAGMIPG------------------VSHEGGEKK------ 289

  Fly   342 VPLLEPMESTRSCQMQTLYIDFKDLGWHDWIIAPEGYGAFYCSGECNFPLNAHMNATNHAIVQTL 406
             ||         |:...:::||..:||.|||:.|:.|.|:.|.|.|..|::.....||||.:|:|
Zfish   290 -PL---------CKKVDMWVDFDQIGWSDWIVYPKRYNAYRCEGSCPTPVDETFTPTNHAYMQSL 344

  Fly   407 VHLLEPKKVPKPCCAPTRLGALPVLYHLNDENVNLKKYRNMIVKSCGCH 455
            :.|..|.:||...|.||||..|.:||:.|.:.| ::.:..|:|..||||
Zfish   345 LKLHHPDRVPCLSCVPTRLAPLSMLYYENGKMV-MRHHEGMVVAECGCH 392

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
gbb	NP_477340.1	TGFb_propeptide	45..305	CDD:459906	41/222 (18%)
		TGF_beta_BMP5_like	353..455	CDD:381639	39/101 (39%)
ndr1	NP_571041.1	TGFb_propeptide	56..190	CDD:480997	29/126 (23%)
		TGF_beta_NODAL	290..392	CDD:381637	41/111 (37%)