Protein Alignment gbb and mstnb

DIOPT Version :10

• Sequence 1: NP_477340.1
• Gene: gbb / 37778
• FlyBaseID: FBgn0024234
• Length: 455
• Species: Drosophila melanogaster
• Sequence 2: NP_571094.2
• Gene: mstnb / 798441
• ZFINID: ZDB-GENE-990415-165
• Length: 374
• Species: Danio rerio
• Alignment Length: 403
• Identity: 100/403 - (24%)
• Similarity: 154/403 - (38%)
• Gaps: 98/403 - (24%)

  Fly    64 VSYEILEFLGIAERPTHLSSHQLSLRKSAPKF--LLDVYHRITAEEGLSDQDEDDDYERGHRSRR 126
            :..:||..|.:.:.|.........|...||..  |||.|      :.|.|..:|...|
Zfish    57 IKSQILSKLRLKQAPNISRDVVKQLLPKAPPLQQLLDQY------DVLGDDSKDGAVE------- 108

  Fly   127 SADLEEDEGEQQKNFITDLDKRAIDESDIIMTFLNKRHHNVDELRHEHGRRLWFDVSNVPNDNYL 191
                |:||....:..:|     ...|.|.|:        .||    ...:..:|..|.....|.:
Zfish   109 ----EDDEHATTETIMT-----MATEPDPIV--------QVD----RKPKCCFFSFSPKIQANRI 152

  Fly   192 VMAELRIY-QNANEGK--WLTANREFTITVYAIGTGTLGQHTMEPLSSVNTTGDYVGWLELNVTE 253
            |.|:|.:: :.|.|..  :|..:|     :..:..|  |:|.:..| .::.......|..::|.:
Zfish   153 VRAQLWVHLRPAEEATTVFLQISR-----LMPVKDG--GRHRIRSL-KIDVNAGVTSWQSIDVKQ 209

  Fly   254 GLHEWLVKSKDNHGIYIGAHAVNRPDREVKLDDIGLIHRKVDDEFQPFM-IGFFRGPELIKATA- 316
            .|..||.:.:.|.||.|.|:.....|..|...:.|      :|...||| :....||:.|:..:
Zfish   210 VLTVWLKQPETNRGIEINAYDAKGNDLAVTSTETG------EDGLLPFMEVKISEGPKRIRRDSG 268

  Fly   317 -----HSSHHRSKRSASHPRKRKKSVSPNNVPLLEPMESTRSCQMQTLYIDFKDLGWHDWIIAPE 376
                 :||..|                               |....|.:||:|.|| ||||||:
Zfish   269 LDCDENSSESR-------------------------------CCRYPLTVDFEDFGW-DWIIAPK 301

  Fly   377 GYGAFYCSGECNFPLNAHMNATNHAIVQTLVHLLEPKKVPKPCCAPTRLGALPVLYHLNDENVNL 441
            .|.|.||||||::   .::....|.   .||:...|:....|||.||::..:.:||....|.:..
Zfish   302 RYKANYCSGECDY---MYLQKYPHT---HLVNKASPRGTAGPCCTPTKMSPINMLYFNGKEQIIY 360

  Fly   442 KKYRNMIVKSCGC 454
            .|..:|:|..|||
Zfish   361 GKIPSMVVDRCGC 373

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
gbb	NP_477340.1	TGFb_propeptide	45..305	CDD:459906	55/246 (22%)
		TGF_beta_BMP5_like	353..455	CDD:381639	39/102 (38%)
mstnb	NP_571094.2	TGFb_propeptide	46..252	CDD:480997	53/242 (22%)
		TGF_beta_GDF8	267..374	CDD:381658	42/145 (29%)