Protein Alignment gbb and Bmp8a

DIOPT Version :9

• Sequence 1: NP_001286786.1
• Gene: gbb / 37778
• FlyBaseID: FBgn0024234
• Length: 455
• Species: Drosophila melanogaster
• Sequence 2: NP_001102902.1
• Gene: Bmp8a / 680931
• RGDID: 1585858
• Length: 399
• Species: Rattus norvegicus
• Alignment Length: 426
• Identity: 143/426 - (33%)
• Similarity: 212/426 - (49%)
• Gaps: 75/426 - (17%)

  Fly    50 TIMHRVLSEDDKLDVSYEILEFLGIAERPTHLSSHQLSLR-KSAPKFLLDVYHRITAEEGLSDQD 113
            |...|.|...::.|:..|||..||:..||...:....:.: .|||.|:||:||.:|
  Rat    29 TCPQRRLGARERRDMQREILAVLGLPGRPRPRAPPAAARQPASAPLFMLDLYHAMT--------- 84

  Fly   114 EDDDYERGHRSRRSADLEEDEGEQQKNFITDLDKRAIDESDIIMTFLN--KRHHNVDELRHEHGR 176
             |||               |.|..|.:         :..:|::|:|:|  :|...:. .:..|.:
  Rat    85 -DDD---------------DGGPPQAH---------LGRADLVMSFVNMVERDRTLG-YQEPHWK 123

  Fly   177 RLWFDVSNVPNDNYLVMAELRIYQNANEGKWLTANREFTITVYAIGTGTLGQHT------MEPLS 235
            ...||::.:|....:..||.|||:   |......|....|:::.:......:.:      ::.|.
  Rat   124 EFHFDLTQIPAGEAVTAAEFRIYK---EPSTHPPNTTLHISMFEVVQERSNRESDLFFLDLQTLR 185

  Fly   236 SVNTTGDYVGWLELNVTEGLHEWLVKSKDNHGIYIGAHAVNRPDREVKLDD--IGLIHRKVDDEF 298
            |    || .|||.|::|.....||:    ||...:|.......:....||.  .||:.:......
  Rat   186 S----GD-EGWLVLDITAASDRWLL----NHNKDLGLRLYVETEDGHSLDPGLAGLLGQTAPRSR 241

  Fly   299 QPFMIGFFRGPELIKATAHSSHHRSKRSA-----SHPRKRKKSVSPNNVP-LLEPMESTRS---C 354
            ||||:.|||        |.||..|:.|:.     ..|:|..:...||.:| :.:....:|.   |
  Rat   242 QPFMVTFFR--------ASSSPVRTPRAVRPLKRRQPKKTNELPHPNKLPGIFDDGHGSRGREVC 298

  Fly   355 QMQTLYIDFKDLGWHDWIIAPEGYGAFYCSGECNFPLNAHMNATNHAIVQTLVHLLEPKKVPKPC 419
            :...||:.|:||||.||:|||:||.|:||.|||.|||::.||||||||:|:||||::|..|||.|
  Rat   299 RRHELYVSFRDLGWLDWVIAPQGYSAYYCEGECAFPLDSCMNATNHAILQSLVHLMKPDVVPKAC 363

  Fly   420 CAPTRLGALPVLYHLNDENVNLKKYRNMIVKSCGCH 455
            ||||:|.|..|||:.:..||.|:|:|||:||:||||
  Rat   364 CAPTKLSATSVLYYDSSNNVILRKHRNMVVKACGCH 399

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
gbb	NP_001286786.1	TGFb_propeptide	44..305	CDD:279078	65/265 (25%)
		TGFB	354..455	CDD:214556	62/100 (62%)
Bmp8a	NP_001102902.1	TGFb_propeptide	32..248	CDD:279078	64/262 (24%)
		TGF_beta	298..398	CDD:278448	61/99 (62%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	1	1.000	172	1.000	Domainoid score	I3618
eggNOG	1	0.900	-	-		E1_KOG3900
Hieranoid	1	1.000	-	-
Homologene	0	0.000	Not matched by this tool.
Inparanoid	1	1.050	260	1.000	Inparanoid score	I3028
OMA	1	1.010	-	-		QHG47130
OrthoDB	1	1.010	-	-		D1063560at2759
OrthoFinder	1	1.000	-	-		FOG0000576
OrthoInspector	1	1.000	-	-		otm46154
orthoMCL	0	0.000	Not matched by this tool.
Panther	1	1.100	-	-	O	PTHR11848
Phylome	1	0.910	-	-
SonicParanoid	1	1.000	-	-		X157
SwiftOrtho	1	1.000	-	-
TreeFam	0	0.000	Not matched by this tool.
	12	11.980