Protein Alignment gbb and Bmp8b

DIOPT Version :9

• Sequence 1: NP_001286786.1
• Gene: gbb / 37778
• FlyBaseID: FBgn0024234
• Length: 455
• Species: Drosophila melanogaster
• Sequence 2: XP_002729572.1
• Gene: Bmp8b / 679119
• RGDID: 1591873
• Length: 399
• Species: Rattus norvegicus
• Alignment Length: 430
• Identity: 136/430 - (31%)
• Similarity: 204/430 - (47%)
• Gaps: 90/430 - (20%)

  Fly    53 HRVLSEDDKLDVSYEILEFLGIAERP---THLSSHQLSLRKSAPKFLLDVYHRITAEEGLSDQDE 114
            || |...:..|:..||.|.||:..||   ..|::.|..  .|||.|:|::||.:|.:.|
  Rat    33 HR-LGVREPRDMQREIREVLGLPGRPRSRAPLATAQQP--ASAPLFMLNLYHAMTDDSG------ 88

  Fly   115 DDDYERGHRSRRSADLEEDEGEQQKNFITDLDKRAIDESDIIMTFLN-KRHHNVDELRHEHGRRL 178
                               .|..|.:         :..:|:||:|:| ..|......:..|.:..
  Rat    89 -------------------NGPPQPH---------LHRADLIMSFVNIVEHDRTLGYQEPHWKEF 125

  Fly   179 WFDVSNVPNDNYLVMAELRIYQNANEGKWLTANREFTITVYAIGTGTLGQHT------MEPLSSV 237
            .||::.:|....:..||.|||:   |......|....|:::.:......:.:      ::.|.|
  Rat   126 HFDLTQIPAGEAVTAAEFRIYK---EPSTHPPNTTLHISMFEVVQERSNRESDLFFLDLQTLRS- 186

  Fly   238 NTTGDYVGWLELNVTEGLHEWLVKSKDNHGIYIGAHAVNRPDREVKLDD--IGLIHRKVDDEFQP 300
               || .|||.|::|.....||:    ||...:|.......:....||.  .||:.:......||
  Rat   187 ---GD-EGWLVLDITAASDRWLL----NHNKDLGLRLYVETEDGHSLDPGLAGLLGQTAPRSRQP 243

  Fly   301 FMIGFFRGPELIKATAHSSHHRSKRSASHPRKRKKSVSPNNVPLLEPMESTRS------------ 353
            ||:|||:        |..|..|:.|:| .|.|:||....|.:|     .|.:.
  Rat   244 FMVGFFK--------ASQSPVRAPRTA-RPLKKKKLNQVNQLP-----NSNKHLGIFDDGHGSLD 294

  Fly   354 ---CQMQTLYIDFKDLGWHDWIIAPEGYGAFYCSGECNFPLNAHMNATNHAIVQTLVHLLEPKKV 415
               |:...||:.|:||||.|.:|||:||.|:||:|||.:|||:.||:||||.:|.||||::|..|
  Rat   295 REVCRRHELYVSFRDLGWLDSVIAPQGYSAYYCAGECIYPLNSCMNSTNHATMQALVHLMKPDIV 359

  Fly   416 PKPCCAPTRLGALPVLYHLNDENVNLKKYRNMIVKSCGCH 455
            ||.||.||:|.|:.:||:..:.||.|::.|||:|::||||
  Rat   360 PKVCCVPTKLSAISLLYYDRNNNVILRRERNMVVQACGCH 399

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
gbb	NP_001286786.1	TGFb_propeptide	44..305	CDD:279078	64/263 (24%)
		TGFB	354..455	CDD:214556	55/100 (55%)
Bmp8b	XP_002729572.1	TGFb_propeptide	32..248	CDD:279078	64/263 (24%)
		TGF_beta	298..398	CDD:278448	54/99 (55%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	1	1.000	92	1.000	Domainoid score	I7404
eggNOG	1	0.900	-	-		E1_KOG3900
Hieranoid	1	1.000	-	-
Homologene	0	0.000	Not matched by this tool.
Inparanoid	1	1.050	260	1.000	Inparanoid score	I3028
OMA	1	1.010	-	-		QHG47130
OrthoDB	1	1.010	-	-		D1063560at2759
OrthoFinder	1	1.000	-	-		FOG0000576
OrthoInspector	1	1.000	-	-		otm46154
orthoMCL	0	0.000	Not matched by this tool.
Panther	1	1.100	-	-	O	PTHR11848
Phylome	1	0.910	-	-
SonicParanoid	1	1.000	-	-		X157
SwiftOrtho	1	1.000	-	-
TreeFam	1	0.960	-	-
	13	12.940