Protein Alignment gbb and bmp7.2

DIOPT Version :9

• Sequence 1: NP_001286786.1
• Gene: gbb / 37778
• FlyBaseID: FBgn0024234
• Length: 455
• Species: Drosophila melanogaster
• Sequence 2: XP_017947617.1
• Gene: bmp7.2 / 619363
• XenbaseID: XB-GENE-855954
• Length: 436
• Species: Xenopus tropicalis
• Alignment Length: 457
• Identity: 148/457 - (32%)
• Similarity: 245/457 - (53%)
• Gaps: 48/457 - (10%)

  Fly    12 AVLASLGLGMVLLMFVATTPPAVEATQSGIYIDNGKDQTIMHRVLSEDDKLDVSYEILEFLGIAE 76
            |::....|.::|.:|..    ::.:..|...::|....:.:.|.|...::.::..|||..||:..
 Frog    15 ALIVKRRLPVLLFLFYI----SLSSISSNTILENDFHSSFVQRRLKGHERREIQKEILTILGLQH 75

  Fly    77 RPTHLSSHQLSLRKSAPKFLLDVYHRITAEEGLSDQDEDDDYERGHRSRRSADLEEDEGEQQKNF 141
            ||......:   :||||.|::|:|:.:..|:   ...||..|     ..:...|.|     ..:.
 Frog    76 RPRPYLPEK---KKSAPLFMMDLYNAVNIED---LNAEDVSY-----FNKPVSLNE-----HSSL 124

  Fly   142 ITDLDKRAIDESDIIMTFLNKRHHNVDELRHEHGRRLWFDVSNVPNDNYLVMAELRIYQNANEGK 206
            .||.:...:..:|.:|:|.| ...|.:|| :::.::..||::::|..:.|..||.|||::
 Frog   125 ATDQENDFLAHADTVMSFAN-LVENDNEL-YKNRQKFKFDLTDIPLGDELTAAEFRIYKD----- 182

  Fly   207 WLTANREFTITVYAIGTGTLGQHTMEP----LSSVNTTGDYVGWLELNVTEGLHEWLVKSKDNHG 267
            ::..|..:.:|||.:   ...|:..||    :.|....|...|||..::|...:.|::....|.|
 Frog   183 YVENNETYQVTVYQV---LQKQYDKEPYLFQVDSRTIWGTEKGWLTFDITATSNHWVINPHYNLG 244

  Fly   268 IYIGAHAVNRPDREVKLDDIGLIHRKVDDEFQPFMIGFFRGPEL----IKATAHSSHHRSKRSAS 328
            :.:...:::.  :.|....:||..|....:.||||:.||:..|:    |::|: :.|...:|:.:
 Frog   245 LQLSIESMDM--QSVNPRHVGLFGRNGPQDKQPFMVAFFKTSEIHLRSIRSTS-NKHWNQERAKT 306

  Fly   329 HPRKRKKSVSPNNV-----PLLEPMESTRSCQMQTLYIDFKDLGWHDWIIAPEGYGAFYCSGECN 388
            :  |.:.:..|.|:     |..:.....::|:...|::.|:||||.|||||||||.|:||.|||.
 Frog   307 Y--KEQDNFPPANISDGIMPTAKRRFFKQACKKHELFVSFRDLGWQDWIIAPEGYAAYYCDGECA 369

  Fly   389 FPLNAHMNATNHAIVQTLVHLLEPKKVPKPCCAPTRLGALPVLYHLNDENVNLKKYRNMIVKSCG 453
            ||||:.||||||||||||||.:.|:.|||||||||:|..:.|||..:..||.||||:||:|::||
 Frog   370 FPLNSFMNATNHAIVQTLVHFVNPETVPKPCCAPTQLNGISVLYFDDSSNVILKKYKNMVVQACG 434

  Fly   454 CH 455
            ||
 Frog   435 CH 436

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
gbb	NP_001286786.1	TGFb_propeptide	44..305	CDD:279078	65/264 (25%)
		TGFB	354..455	CDD:214556	65/100 (65%)
bmp7.2	XP_017947617.1	TGFb_propeptide	44..280	CDD:395559	65/263 (25%)
		TGF_beta_BMP7	330..436	CDD:381667	65/105 (62%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	1	1.000	172	1.000	Domainoid score	I3678
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	1	1.000	-	-
Homologene	0	0.000	Not matched by this tool.
Inparanoid	1	1.050	259	1.000	Inparanoid score	I3042
OMA	1	1.010	-	-		QHG47130
OrthoDB	1	1.010	-	-		D1063560at2759
OrthoFinder	1	1.000	-	-		FOG0000576
OrthoInspector	1	1.000	-	-		otm49237
Panther	1	1.100	-	-	O	PTHR11848
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	1	1.000	-	-		X157
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	10	10.080