Protein Alignment gbb and tgfb1b

DIOPT Version :9

• Sequence 1: NP_001286786.1
• Gene: gbb / 37778
• FlyBaseID: FBgn0024234
• Length: 455
• Species: Drosophila melanogaster
• Sequence 2: XP_692338.3
• Gene: tgfb1b / 563884
• ZFINID: ZDB-GENE-091028-1
• Length: 379
• Species: Danio rerio
• Alignment Length: 436
• Identity: 95/436 - (21%)
• Similarity: 174/436 - (39%)
• Gaps: 113/436 - (25%)

  Fly    54 RVLSEDDKLDVSY-----------EILEFLGIAERPTHLSSHQLSLRKSAPKFLLDVYH---RIT 104
            |.||..:.||:..           :||..|.:.:.|   ...:..|.::.|..|:.||:   .:.
Zfish    21 RALSTCNPLDLELIKRKRIEAIRGQILSKLRLPKEP---EVEEKELIENIPAELISVYNSTMELN 82

  Fly   105 AEEG-------LSDQDEDDDYERG-HRSRRSADLEEDEGEQQKNFITDLDKRAIDESDIIMTFLN 161
            .|:.       :.|..|::.|.:. |:    ..:.|::.|:...|
Zfish    83 EEQAANPVQHTIEDPTEEEYYAKEIHK----FTMMEEKPEKYLVF-------------------- 123

  Fly   162 KRHHNVDELRHEHGRRLWFDVSNVPNDNYLVMAELRIYQNANEGKWLTANREFTITVYAIGTGTL 226
                |:.:::|:.|.           ::.|..||.|:  ...|.|  ..:.|..:.:|.: ||..
Zfish   124 ----NITDIKHKLGA-----------NHVLYQAEFRL--RIKEPK--MGDSEQRLELYQV-TGNK 168

  Fly   227 GQHTMEPLSSVNTTGDYVGWLELNVTEGLHEWLVKSKDNHGIYIGAHAVNRPDRE-----VKL-- 284
            .::......|:.|.|.   |:..:||..|.:||...::.....:......:|:.:     .|:
Zfish   169 SRYLNSRFISLQTAGK---WVSFDVTSTLKDWLQMPEEKQEFQLQLACSCKPESQNTEFLFKIAG 230

  Fly   285 -----DDIGLIHRKVDDEFQPFMIGFFRGPELIKATAHSSHHRSKRSASHPRKRKKSVSPNNVPL 344
                 .|.||:   .|...:|:::..             ||.....|.:..|:::::.:...
Zfish   231 LSRNRGDTGLL---ADQVAKPYILVM-------------SHPADGHSPAKSRRKRETDAVCT--- 276

  Fly   345 LEPMESTRSCQMQTLYIDF-KDLGWHDWIIAPEGYGAFYCSGECNFPLNAHMNATNHAIVQTLVH 408
                |.:..|.:::||||| ||||| .||..|.||.|.||:|.|::   ...:...::.|..|..
Zfish   277 ----EKSEGCCVRSLYIDFRKDLGW-KWIHEPSGYYANYCTGSCSY---VWTSENKYSQVLALYR 333

  Fly   409 LLEPKKVPKPCCAPTRLGALPVLYHLNDENVNLKKYRNMIVKSCGC 454
            ...|....:|||.|..|..||::|::..:: .:::..|||||:|.|
Zfish   334 HHNPGASAQPCCVPQVLDPLPIIYYVGRQH-KVEQLSNMIVKTCKC 378

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
gbb	NP_001286786.1	TGFb_propeptide	44..305	CDD:279078	51/284 (18%)
		TGFB	354..455	CDD:214556	39/102 (38%)
tgfb1b	XP_692338.3	TGFb_propeptide	22..253	CDD:279078	50/283 (18%)
		TGF_beta	280..378	CDD:278448	38/102 (37%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	1	1.000	-	-
TreeFam	0	0.000	Not matched by this tool.
ZFIN	0	0.000	Not matched by this tool.
	2	1.910