Protein Alignment gbb and gdf2

DIOPT Version :9

• Sequence 1: NP_001286786.1
• Gene: gbb / 37778
• FlyBaseID: FBgn0024234
• Length: 455
• Species: Drosophila melanogaster
• Sequence 2: NP_001165057.2
• Gene: gdf2 / 563287
• ZFINID: ZDB-GENE-100107-1
• Length: 389
• Species: Danio rerio
• Alignment Length: 457
• Identity: 111/457 - (24%)
• Similarity: 175/457 - (38%)
• Gaps: 156/457 - (34%)

  Fly    51 IMHRVLSEDDKLDVSYEILEFLGIAE----RPTHLSSHQLSLRK-SAPKFLLDVYHRITAEEGLS 110
            |..:.|.|||.|:   ::..|||..:    |..:||......|| ..|:|::::|:|..:
Zfish    35 IQEQKLVEDDDLN---KVESFLGFMKEDFLRKLNLSGVPQEHRKVQPPQFMIELYNRYAS----- 91

  Fly   111 DQDEDDDYERGHRSRRSADLEEDEGEQQKNFITDLDKRAIDESDIIMTFL-----------NKRH 164
                                               ||.:|..||:|.:|:           ||..
Zfish    92 -----------------------------------DKNSIPRSDVIRSFVVQDVIYSIRQGNKTQ 121

  Fly   165 HNVDELRHEHGRRLWFDVSNVPNDNYLVMAELRIYQNANEGKWLTANREFTITVYAI----GTGT 225
            |           ||.|:|| :||...:...:||::...:..|....:...:|.||.:    ....
Zfish   122 H-----------RLLFNVS-IPNHEEITSVQLRLFTLWHRHKPACDDLFTSINVYDVEYEQNAKI 174

  Fly   226 L----GQHTMEPLSSVNTTGDYVGWLELNVTEGLHEWLVKSKDNHGIYIGAHAVNRPDREVKLD- 285
            |    |:...|   |:||      |...:||..:..|              |...|...|::::
Zfish   175 LHLLDGRDVRE---SINT------WEAFDVTGAVRIW--------------HESRRGAGEIQVEV 216

  Fly   286 -------DIGLIHRKVDDEFQPFMIGFF------------RGPELIKATAHSSHHRSKRSASHPR 331
                   ||.|   .::|.....:|.|.            :..|::........:::..|..|.|
Zfish   217 QHSCDSFDISL---SLEDNSSAVVIVFSDDLGNRKEESMRKVKEMLVREQQQVGNQAPVSNRHRR 278

  Fly   332 KRKKSVSPNNVPLLEPMESTRSCQMQTLYIDFKDLGWHDWIIAPEGYGAFYCSGECNFPLNAHMN 396
            :::|  :.||.           |:..:|.::|||:||..||:||..|.|:.|.|.|.|||...::
Zfish   279 RKRK--AKNNY-----------CRRTSLKVNFKDIGWDKWIVAPPEYDAYECKGVCYFPLTDDVS 330

  Fly   397 ATNHAIVQTLVHLLEPKKVPKPCCAPTRLGALPVLY---------HLNDENVNLKKYRNMIVKSC 452
            .:.||::||||:|..|||....||.||:|..:.|:|         ||         |..|.|..|
Zfish   331 PSRHAVIQTLVNLSNPKKANMACCVPTKLDPIAVMYQEKGVITVRHL---------YEEMKVAKC 386

  Fly   453 GC 454
            ||
Zfish   387 GC 388

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
gbb	NP_001286786.1	TGFb_propeptide	44..305	CDD:279078	59/285 (21%)
		TGFB	354..455	CDD:214556	44/110 (40%)
gdf2	NP_001165057.2	TGFb_propeptide	60..222	CDD:279078	45/236 (19%)
		Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite	263..284		4/22 (18%)
		TGF_beta	288..388	CDD:278448	42/108 (39%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_KOG3900
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
ZFIN	0	0.000	Not matched by this tool.
	2	1.810