Protein Alignment gbb and tgfb5

DIOPT Version :9

• Sequence 1: NP_001286786.1
• Gene: gbb / 37778
• FlyBaseID: FBgn0024234
• Length: 455
• Species: Drosophila melanogaster
• Sequence 2: XP_021336789.1
• Gene: tgfb5 / 559723
• ZFINID: ZDB-GENE-130425-3
• Length: 414
• Species: Danio rerio
• Alignment Length: 320
• Identity: 87/320 - (27%)
• Similarity: 134/320 - (41%)
• Gaps: 76/320 - (23%)

  Fly   176 RRLWFDVSNVP-NDNYLVMAELRIYQNANEGKWLTANREFTITVYAI---------GTGTLGQHT 230
            |.:.|||:||. |.:.||.||.||::..|.....|..|   :.:|.|         ....:...|
Zfish   129 RIVGFDVTNVERNSSTLVKAEFRIFRAPNPQARATEQR---VEIYQILKSEDVTAPSQRYIDSRT 190

  Fly   231 MEPLSSVNTTGDYVGWLELNVTEGLHEWLVKSKDNHGIYIGAHA------------VNRPDREVK 283
            :||.:.       ..||.::|||.:.||:...:.|.|:.|..|.            |.....|::
Zfish   191 VEPRAK-------GAWLSVDVTETVKEWMAFRERNLGLKISVHCPCCTFVPSTNNIVPNKSEELE 248

  Fly   284 LDDIGLIHRKVDDEF--QPFMIGFFRG--------PELI-------KATAHSSHHRSKRSASHPR 331
            ....|     :||:.  |....|..:|        |.||       :..:.....|.||||:
Zfish   249 ARFAG-----IDDDLIKQTRKPGVTKGQIEFSTKTPHLILTLLPTDRLDSPIKKTRKKRSAA--- 305

  Fly   332 KRKKSVSPNNVPLLEPMESTRSCQMQTLYIDF-KDLGWHDWIIAPEGYGAFYCSGECNFPLNAHM 395
              ..|:...|         .:.|.:::||||| :||.| .||..|:||.|.:|:|.|.:    ..
Zfish   306 --DTSICTRN---------DQGCCLRSLYIDFRRDLNW-KWIHEPKGYKANFCAGNCPY----LW 354

  Fly   396 NATNH-AIVQTLVHLLEPKKVPKPCCAPTRLGALPVLYHLNDENVNLKKYRNMIVKSCGC 454
            :|.|| .::..|.:.:.|:....|||.|..|..|.::|.|. ....:::..||:|:||.|
Zfish   355 SADNHYNMILPLYNKMNPEASASPCCVPQDLEPLTIVYFLG-RTPRVEQLSNMVVRSCKC 413

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
gbb	NP_001286786.1	TGFb_propeptide	44..305	CDD:279078	38/152 (25%)
		TGFB	354..455	CDD:214556	37/103 (36%)
tgfb5	XP_021336789.1	TGFb_propeptide	21..229	CDD:307025	32/109 (29%)
		TGF_beta	317..413	CDD:306518	36/101 (36%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_KOG3900
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	1	1.000	-	-
TreeFam	0	0.000	Not matched by this tool.
ZFIN	0	0.000	Not matched by this tool.
	3	2.810