Protein Alignment gbb and bmp2

DIOPT Version :9

• Sequence 1: NP_001286786.1
• Gene: gbb / 37778
• FlyBaseID: FBgn0024234
• Length: 455
• Species: Drosophila melanogaster
• Sequence 2: NP_001015963.1
• Gene: bmp2 / 548717
• XenbaseID: XB-GENE-481829
• Length: 398
• Species: Xenopus tropicalis
• Alignment Length: 449
• Identity: 132/449 - (29%)
• Similarity: 208/449 - (46%)
• Gaps: 120/449 - (26%)

  Fly    42 YIDNGK-----DQTIMHRVLSEDDKLDVSYEILEFLGIAERPTHLSSHQLSLRKSAPKFLLDVYH 101
            |.::|:     .|:::::         ....:|...|:..|||...:..:      |.::||:||
 Frog    33 YTESGRSSPQHSQSVLNQ---------FELRLLNMFGLKRRPTPGKNIVI------PPYMLDLYH 82

  Fly   102 RITAEEGLSDQDEDD-DYERGHRSRRSADLEEDEGEQQKNFITDLDKRAIDESDIIMTFLNKRHH 165
             :.:.:..:|||... ||:                          .:||...::.:.:|    ||
 Frog    83 -LHSGQLAADQDSSPMDYQ--------------------------IERAASRANTVRSF----HH 116

  Fly   166 --NVDELRHEHG----RRLWFDVSNVPNDNYLVMAELRIY----QNANEGKWLTANREFTITVYA 220
              :::|: .|.|    :|.:|::|:|||:..:..|||||:    |...||   .:::...|.:|.
 Frog   117 EESMEEI-PESGEKTIQRFFFNLSSVPNEELVTSAELRIFREGVQEPFEG---DSSKLHRINIYD 177

  Fly   221 IGTGTLGQHTMEPLSSVNTTGDYV-------------GWLELNVTEGLHEWLVKSKDNHGIYIG- 271
            |         ::|.::. :.|..|             .|...:||..:..|:...:.|||..:.
 Frog   178 I---------VKPAAAA-SRGPVVRLLDTRLIHHNESKWESFDVTPAITRWIAHKQPNHGFVVEV 232

  Fly   272 AHAVNRPDREVKLDDIGLIHRKVDDE-----FQPFMIGFFRGPELIKATAHSSHHRSKRSASH-P 330
            .|..|  |:.|....:.:....|.|:     .:|.::.|..     ....|:.|.|.||.|.| .
 Frog   233 THLDN--DKNVPKKHVRISRSLVPDKDSWPRIRPLLVTFSH-----DGKGHALHKREKRQARHKQ 290

  Fly   331 RKRKKSVSPNNVPLLEPMESTRSCQMQTLYIDFKDLGWHDWIIAPEGYGAFYCSGECNFPLNAHM 395
            |||.||                ||:...||:||.|:||:|||:||.||.||||.|||.|||..|:
 Frog   291 RKRLKS----------------SCRRHPLYVDFSDVGWNDWIVAPPGYHAFYCHGECPFPLADHL 339

  Fly   396 NATNHAIVQTLVHLLEPKKVPKPCCAPTRLGALPVLYHLNDENVNLKKYRNMIVKSCGC 454
            |:||||||||||:.:.| .:||.||.||.|.|:.:||...:|.|.||.|::|:|:.|||
 Frog   340 NSTNHAIVQTLVNNVNP-NIPKACCVPTELSAISMLYLDENEKVVLKNYQDMVVEGCGC 397

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
gbb	NP_001286786.1	TGFb_propeptide	44..305	CDD:279078	59/295 (20%)
		TGFB	354..455	CDD:214556	58/101 (57%)
bmp2	NP_001015963.1	TGFb_propeptide	34..269	CDD:366248	59/296 (20%)
		TGF_beta_BMP2_like	298..398	CDD:381638	58/101 (57%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	1	1.000	-	-		X157
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	2	1.910