Protein Alignment gbb and bmp6

DIOPT Version :9

• Sequence 1: NP_001286786.1
• Gene: gbb / 37778
• FlyBaseID: FBgn0024234
• Length: 455
• Species: Drosophila melanogaster
• Sequence 2: NP_001013357.1
• Gene: bmp6 / 503761
• ZFINID: ZDB-GENE-050306-42
• Length: 417
• Species: Danio rerio
• Alignment Length: 414
• Identity: 149/414 - (35%)
• Similarity: 229/414 - (55%)
• Gaps: 40/414 - (9%)

  Fly    52 MHRVLSEDDKLDVSYEILEFLGIAERP-THLSSHQLSLRKSAPKFLLDVYHRITAEEGLSDQDED 115
            :||.|...:|.::..|||..||:..|| .||:|.:.:   |||.|:||:|:.::.||    :.:.
Zfish    34 IHRRLRSQEKREMQKEILSILGLNHRPRPHLNSGKYN---SAPLFMLDLYNSMSTEE----KSDV 91

  Fly   116 DDYERGHRSRRSADLEEDEGEQQKNFITDLDKRAIDESDIIMTFLNKRHHNVD-ELRHEHGRRLW 179
            |.|.....:.|.|            ..:..|...:.::|::|:|:|...::.: .|:..|.:...
Zfish    92 DQYRSLFTTTRPA------------LASHHDTEFLHDADMVMSFVNLVENDRELSLQRRHHKEFK 144

  Fly   180 FDVSNVPNDNYLVMAELRIYQNANEGKWLTANREFTITVYAIGTGTLGQH-----TMEPLSSVNT 239
            |::|.:|....:..||.|||:......:  .|..|.::|:.:    :|:|     .:..|.|...
Zfish   145 FNLSQIPEGEAITAAEFRIYKECVTSAF--RNETFLLSVFQV----VGEHPDRDADLFLLESRRL 203

  Fly   240 TGDYVGWLELNVTEGLHEWLVKSKDNHGIYIGAHAVNRPDREVKLDDIGLIHRKVDDEFQPFMIG 304
            .|...||||.::|...:.|::....|.|:.|.....:  .|.:...|.||:.|....|.||||:.
Zfish   204 WGAEQGWLEFDITATSNLWVMSPHHNLGLQISVETSS--GRSISPKDAGLVGRDGALERQPFMVA 266

  Fly   305 FFRGPELIKATAHSS---HHRSKRSASHPRKRKKSVSPNNVPLLEPMESTRSCQMQTLYIDFKDL 366
            ||:..|:...|:.|:   ..|::..::.|::..|..:..:   ....:...:|:...||:.|::|
Zfish   267 FFKVSEVRIRTSRSTGKQRQRNRNRSNSPQEASKGPAHTD---YNSSDQKTACRKHDLYVSFREL 328

  Fly   367 GWHDWIIAPEGYGAFYCSGECNFPLNAHMNATNHAIVQTLVHLLEPKKVPKPCCAPTRLGALPVL 431
            .|.|||||||||.|.||.|||:|||||||||||||||||||||:.|:.|||||||||:|.|:.||
Zfish   329 SWQDWIIAPEGYAANYCDGECSFPLNAHMNATNHAIVQTLVHLMNPENVPKPCCAPTKLHAISVL 393

  Fly   432 YHLNDENVNLKKYRNMIVKSCGCH 455
            |:.::.||.|||||||:|:|||||
Zfish   394 YYDDNSNVILKKYRNMVVRSCGCH 417

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
gbb	NP_001286786.1	TGFb_propeptide	44..305	CDD:279078	69/259 (27%)
		TGFB	354..455	CDD:214556	70/100 (70%)
bmp6	NP_001013357.1	TGFb_propeptide	28..267	CDD:279078	69/259 (27%)
		TGFB	316..417	CDD:214556	70/100 (70%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	1	1.000	172	1.000	Domainoid score	I3669
eggNOG	1	0.900	-	-		E1_KOG3900
Hieranoid	1	1.000	-	-
Homologene	0	0.000	Not matched by this tool.
Inparanoid	1	1.050	256	1.000	Inparanoid score	I3143
OMA	0	0.000	Not matched by this tool.
OrthoDB	1	1.010	-	-		D1063560at2759
OrthoFinder	1	1.000	-	-		FOG0000576
OrthoInspector	1	1.000	-	-		otm25252
orthoMCL	1	0.900	-	-		OOG6_107058
Panther	1	1.100	-	-	O	PTHR11848
Phylome	1	0.910	-	-
RoundUp	1	1.030	-	avgDist	Average_Evolutionary_Distance	R4460
SonicParanoid	1	1.000	-	-		X157
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	1	0.960	-	-
ZFIN	0	0.000	Not matched by this tool.
	13	12.860