Protein Alignment gbb and Gdf3

DIOPT Version :9

• Sequence 1: NP_001286786.1
• Gene: gbb / 37778
• FlyBaseID: FBgn0024234
• Length: 455
• Species: Drosophila melanogaster
• Sequence 2: NP_001103141.1
• Gene: Gdf3 / 500311
• RGDID: 1564178
• Length: 366
• Species: Rattus norvegicus
• Alignment Length: 397
• Identity: 108/397 - (27%)
• Similarity: 177/397 - (44%)
• Gaps: 67/397 - (16%)

  Fly    66 YEILEFLGIAERPTHLSSHQLSLRKSAPKFLLDVYH-RITAEEGLSDQDEDDDYERGHRSRRSAD 129
            |:.|:|||:.:.|   |.|:.   :..|:.|..:.. |.||....:.||.....|.|.|. ....
  Rat    28 YDFLQFLGLKKAP---SPHRF---QPVPRILRKIIRARETAAASGASQDLCYVKELGVRG-NLLR 85

  Fly   130 LEEDEGEQQKNFITDLDKRAIDESDIIMTFLNKRHHNVDELRHEHGRRLWFDVSNVPNDNYLVMA 194
            |..|:|     |..:..|.:.|.|.:                   .:.|.|::|.|.....|.||
  Rat    86 LLPDQG-----FFLNTQKPSQDGSCL-------------------QKVLSFNLSAVKEKGKLTMA 126

  Fly   195 ELRIYQNANEGKWLTANREFTITVYAI-GTGTLGQHTMEP-----LSSVNTTGDYVGWLELNVTE 253
            :|.::.......:|  ..|..:.|..: ..|..|:  ..|     |...:..|.. |.|:.|:..
  Rat   127 QLILHLGPRSYHYL--QLELVVAVSVVQDRGVWGR--SHPKLGRLLVQKSVLGPQ-GSLQFNLQG 186

  Fly   254 GLHEWLVKSKDNHGIYIGAHAVNRPDREVKLDDIGLIHRKVDDEFQPFMIGFFRGPELIKATAHS 318
            .:.:|......|..:|:        :..||.|....::.::|:.....|....  ..|:..|.:.
  Rat   187 VVKDWNRHQLKNLDLYL--------EILVKEDRYSRVNAQLDNPCNQLMHSLH--ASLLVVTLNL 241

  Fly   319 SHHRSKRSASHPRKRKKSVSPNNVPLLEPMESTRS-CQMQTLYIDFKDLGWHDWIIAPEGYGAFY 382
            .|       .||..|||..:   :|:  |....|: |....|:::|:|||||.|:|||:|:.|.|
  Rat   242 KH-------CHPSSRKKRAA---IPI--PKGLCRNLCHRHQLFVNFQDLGWHKWVIAPKGFMANY 294

  Fly   383 CSGECNFPLNAHMNATNHAIVQTLVHLLEPKKVPKPCCAPTRLGALPVLYHLNDENVNLKKYRNM 447
            |.|:|.|.:..::|::|:|.:|.|:|:.:| :|||..|.||:|..:.:||..|::||.|:.|.:|
  Rat   295 CHGDCPFTMTTYLNSSNYAFMQALMHMADP-RVPKAVCIPTKLSPISMLYQDNEKNVILRHYEDM 358

  Fly   448 IVKSCGC 454
            :|..|||
  Rat   359 VVDECGC 365

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
gbb	NP_001286786.1	TGFb_propeptide	44..305	CDD:279078	52/245 (21%)
		TGFB	354..455	CDD:214556	45/101 (45%)
Gdf3	NP_001103141.1	TGFB	266..366	CDD:214556	45/101 (45%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_KOG3900
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	1	1.000	-	-
TreeFam	0	0.000	Not matched by this tool.
	3	2.810