Protein Alignment gbb and Lefty1

DIOPT Version :9

• Sequence 1: NP_001286786.1
• Gene: gbb / 37778
• FlyBaseID: FBgn0024234
• Length: 455
• Species: Drosophila melanogaster
• Sequence 2: NP_001102550.1
• Gene: Lefty1 / 498299
• RGDID: 1561867
• Length: 368
• Species: Rattus norvegicus
• Alignment Length: 383
• Identity: 72/383 - (18%)
• Similarity: 129/383 - (33%)
• Gaps: 143/383 - (37%)

  Fly   145 LDKRAIDESDIIMTFLNKRHHNVDELRHEH-----------------GRRLWFDVSN-------- 184
            |||..: |..:|.:.:..::  |..|:|.|                 ||.|..:.|:
  Rat    43 LDKADV-EGMVIPSHVRAQY--VALLQHSHDSRSRGKRFSQNFREVAGRFLVSETSSHLLVFGME 104

  Fly   185 --VPNDNYLVMAELRIYQNANEGKWLTANREFT-------ITVYAIGTGTLGQHTMEPLSSVNTT 240
              :|.::.||.|.||::|.......|...:..:       :|:..:.....|.:....:.|...:
  Rat   105 QRLPPNSELVQAVLRLFQEPVPRTALRRQKRLSPHSARARVTIEWLRFREDGSNRTALIDSRLVS 169

  Fly   241 GDYVGWLELNVTEGLHEWLVKSKDNHGIYIGAHAVNRPDREVKLDDIGLIHRKVDDEFQPFMIGF 305
            ....||...:|||.::.|              ..::||
  Rat   170 IHESGWKVFDVTEAVNFW--------------QQLSRP--------------------------- 193

  Fly   306 FRGPELIKATAHSSH--------HRSKRSASHPRKRKKSVSPNNVPLLEPM-------------- 348
             |.|.|::.:....|        |:..|.|:..       :|:...|.||.
  Rat   194 -RQPLLLQVSVQREHLGPGTWSAHKLVRFAAQG-------TPDGKGLGEPQLELHTLDLKDYGAQ 250

  Fly   349 ----------ESTRSCQMQTLYIDFKDLGW-HDWIIAPEGYGAFYCSGECNFPLNAHMNATNHAI 402
                      |.||.|: |.:|:|.:.:.| .:||:.|.|:..:.|.|.|..|..:
  Rat   251 GNCDPETPVTEGTRCCR-QEMYLDLQGMKWAENWILEPPGFLTYECVGSCLQPPES--------- 305

  Fly   403 VQTLVHLLEPKKVPKPCCAPTRLGALPVLYHLNDEN------VNLKKYRNMIVKSCGC 454
                :.:..|...|:.|.| :.:.:||::..:.::.      |:|.   ||.|:.|.|
  Rat   306 ----LTIRWPFLGPRQCVA-SEMTSLPLIVSIKEDGRTRPQVVSLP---NMRVQRCSC 355

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
gbb	NP_001286786.1	TGFb_propeptide	44..305	CDD:279078	32/193 (17%)
		TGFB	354..455	CDD:214556	26/108 (24%)
Lefty1	NP_001102550.1	TGFb_propeptide	29..211	CDD:413528	36/212 (17%)
		TGF_beta_LEFTY1_2	264..355	CDD:381636	26/108 (24%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_KOG3900
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	2	1.810