Protein Alignment gbb and scw

DIOPT Version :10

• Sequence 1: NP_477340.1
• Gene: gbb / 37778
• FlyBaseID: FBgn0024234
• Length: 455
• Species: Drosophila melanogaster
• Sequence 2: NP_524863.3
• Gene: scw / 46000
• FlyBaseID: FBgn0005590
• Length: 400
• Species: Drosophila melanogaster
• Alignment Length: 442
• Identity: 146/442 - (33%)
• Similarity: 228/442 - (51%)
• Gaps: 49/442 - (11%)

  Fly    21 MVLLMFVATTPPAVEATQSGIYIDNGKDQTI-MHRVLSEDDKLDVSYEILEFLGIAERPTHLSSH 84
            |:.:.|:.:...|..|| :.:..:|..:..| ..|.|||      ..|:::.|.:.:||...:
  Fly     1 MLNVFFLTSLFYAASAT-TYVTTNNHIEMPIYQKRPLSE------QMEMIDILDLGDRPRRQA-- 56

  Fly    85 QLSLRKSAPKFLLDVYHRITAEEGLSDQDEDDDYERGHRSRRSADLEEDEGEQQKNFITDLDKRA 149
            :.:|..||.||||:||:.|:         ||.:.:.....|....|::|      ..|::.|::.
  Fly    57 EPNLHNSASKFLLEVYNEIS---------EDQEPKEVLHQRHKRSLDDD------ILISNEDRQE 106

  Fly   150 IDESDIIMTFLNKRHHNVDELRHEHGRRLWFDVSNVPNDNYLVMAELRIYQNANEGKWLTANR-E 213
            |...:.|:||.::.  ..::|.:|....:.|:.::||.|..||.|.||||:..:    |...| .
  Fly   107 IASCNSILTFSSRL--KPEQLDNELDMHITFNTNDVPVDLSLVQAMLRIYKQPS----LVDRRAN 165

  Fly   214 FTITVYAIGTGTLGQHTMEPLSSVNTTGDYVGWLELNVTEGLHEWL----VKSKDNHGIYIGAHA 274
            ||::||. ........:...|.|||||....||||.|:|:.|..||    ::.::...|.||
  Fly   166 FTVSVYR-KLDNRQDFSYRILGSVNTTSSQRGWLEFNLTDTLRYWLHNKGLQRRNELRISIG--- 226

  Fly   275 VNRPDREVKLDDIGLIHRKVD-DEFQPFMIGFFRGPELIKATAHSSHHRSKRSASHPRKRKKSVS 338
                |.::.....||:..:.. ...:||::|:|.||||:   ......|.||.....|....|..
  Fly   227 ----DSQLSTFAAGLVTPQASRTSLEPFIVGYFNGPELL---VKIQKLRFKRDLEKRRAGGGSPP 284

  Fly   339 PNNVPLLEPMESTRSCQMQTLYIDFKDLGWHDWIIAPEGYGAFYCSGECNFPLNAHMNATNHAIV 403
            |...|.::.....:||:.....:|||:|..|:|:|||:.:.|::|.|.|||||...|||||||||
  Fly   285 PPPPPPVDLYRPPQSCERLNFTVDFKELHMHNWVIAPKKFEAYFCGGGCNFPLGTKMNATNHAIV 349

  Fly   404 QTLVHLLEPKKVPKPCCAPTRLGALPVLYHLNDENVNLKKYRNMIVKSCGCH 455
            |||:||.:| .:|||||.||.|||:.:|.:||::.::|.||:..:.|.||||
  Fly   350 QTLMHLKQP-HLPKPCCVPTVLGAITILRYLNEDIIDLTKYQKAVAKECGCH 400

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
gbb	NP_477340.1	TGFb_propeptide	45..305	CDD:459906	73/266 (27%)
		TGF_beta_BMP5_like	353..455	CDD:381639	53/101 (52%)
scw	NP_524863.3	TGFb_propeptide	39..254	CDD:480997	67/245 (27%)
		TGF_beta_BMP5_like	299..400	CDD:381639	53/101 (52%)