Protein Alignment gbb and myo

DIOPT Version :9

• Sequence 1: NP_001286786.1
• Gene: gbb / 37778
• FlyBaseID: FBgn0024234
• Length: 455
• Species: Drosophila melanogaster
• Sequence 2: NP_726604.1
• Gene: myo / 43811
• FlyBaseID: FBgn0026199
• Length: 598
• Species: Drosophila melanogaster
• Alignment Length: 534
• Identity: 103/534 - (19%)
• Similarity: 200/534 - (37%)
• Gaps: 151/534 - (28%)

  Fly     5 RNTSEAVAVLASLGLGMVLLMFVATTPPAVEATQSGIYIDNG----------------KDQTIMH 53
            :|.|.:::....:...|.:......:.|..::|......::|                ..::::.
  Fly   131 KNGSSSISADDKINENMGIFQMKVQSKPGKKSTPLAKVSEHGDLSRVQSVSLYRNTLINIESMLQ 195

  Fly    54 RVLSEDDKLD----VSYEILEFLGIAERPTHLSSHQLSLRKSAPKFLLDVYHR-ITAEEGLSDQD 113
            |.|.|..|:|    :...||..|.:.:.|      .::...|.|:.::|.::| ..|....:..:
  Fly   196 RQLREKAKVDSIESIKMHILMRLNLKKLP------NITKPISVPQNIIDNFYRDYNASSKTTVWN 254

  Fly   114 EDDDYERGHRS----------------RRSADLEEDEGEQQKNFITDLDKRAIDESDIIMTFLNK 162
            ..:..:..|.|                ..|:.::.|:......|:.||:|....:|||.:...::
  Fly   255 RMESIDESHLSINDTYGDHIMTDFFDESSSSQMQGDDANTVNEFLIDLNKNQAKKSDIPINTNDE 319

  Fly   163 RHHNVDELRH---------------EHGRRL---WFDVSNVPNDNYLVMAELRIYQNANEGKWLT 209
            .:.::  |.|               .|.|::   .|.:.:..:|  |..|.|.:|....:  |::
  Fly   320 EYESI--LSHISSIYIFPEEIQPHVRHNRKVDVFRFQIDSSYSD--LSYATLHLYLRGWD--WIS 378

  Fly   210 ANREFTITVYAIGTGTLGQHTMEPLSSV-----------NTT--GDYVGWLEL--NVTEGLHEWL 259
            |::          .|.|.:...:|...:           |||  ...|...|.  ::..||.:|:
  Fly   379 AHQ----------PGLLEEIKKQPRKDIVVTIHRAIRVANTTSFNPKVKMFEFRHSIPSGLGQWV 433

  Fly   260 VKSKDNHGIYIGAHAVNRPDREVKLDDIGLIHRKVDDEFQPFMIGFFRGPEL-IKATAHSSHHRS 323
                          ||   |.:..|.::|      .:..|..:|   :|.|. :|:...::.:.|
  Fly   434 --------------AV---DLKSLLGNLG------SNMTQEILI---KGAETWMKSLVVTTDNTS 472

  Fly   324 KR--------SASHPRKRKKSVSPNNVPLLEPMESTRS-----CQMQTLYIDFKDLGWHDWIIAP 375
            |.        .:....:||:||.         |:.|.:     |....|.::|...||| :::||
  Fly   473 KNPLTVHIEIGSQKKHRRKRSVY---------MDCTENDHDMRCCRYPLKVNFTSFGWH-FVVAP 527

  Fly   376 EGYGAFYCSGECNFPLNAHMNATNHAIVQTLVHLLEPKKVPKPCCAPTRLGALPVLYHLNDENVN 440
            ..:.|::|||:|..   .::....|      .||........|||:||::.:|.:||..::.|:.
  Fly   528 TSFDAYFCSGDCKV---GYLEQYPH------THLAALTTSATPCCSPTKMSSLSLLYFDDNHNLV 583

  Fly   441 LKKYRNMIVKSCGC 454
            |....||.|:.|.|
  Fly   584 LSVIPNMSVEGCSC 597

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
gbb	NP_001286786.1	TGFb_propeptide	44..305	CDD:279078	56/330 (17%)
		TGFB	354..455	CDD:214556	31/101 (31%)
myo	NP_726604.1	TGF_beta	506..597	CDD:278448	30/100 (30%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	1	0.930	-	-		C45466522
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	1	1.100	-	-	P	PTHR11848
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
	3	2.940