Protein Alignment gbb and bmp7

DIOPT Version :10

• Sequence 1: NP_477340.1
• Gene: gbb / 37778
• FlyBaseID: FBgn0024234
• Length: 455
• Species: Drosophila melanogaster
• Sequence 2: NP_989197.1
• Gene: bmp7 / 394805
• XenbaseID: XB-GENE-486014
• Length: 424
• Species: Xenopus tropicalis
• Alignment Length: 427
• Identity: 152/427 - (35%)
• Similarity: 228/427 - (53%)
• Gaps: 45/427 - (10%)

  Fly    43 IDNGKDQTIMHRVLSEDDKLDVSYEILEFLGIAERP-THLSSHQLSLRKSAPKFLLDVYHRITAE 106
            :||....:.:.|.|...::.::..|||..||:..|| .||...|    .|||.|:||:|:.:|.
 Frog    29 LDNEVHSSFIQRRLRGQERREMQREILSILGLPHRPRPHLYGKQ----NSAPMFMLDLYNAMTV- 88

  Fly   107 EGLSDQDEDDDYERGHRSRRSADLEEDEGEQQKNFITDLDKRAIDESDIIMTFLNKRHHNVDELR 171
                |::|.:.:...::...:........:|..||:.|        :|::|:|:|...|: .|..
 Frog    89 ----DEEEAEGFSYPYKPIFTTQGPPLASQQDSNFLND--------ADMVMSFVNLVEHD-KEFF 140

  Fly   172 HE--HGRRLWFDVSNVPNDNYLVMAELRIYQNANEGKWLTANREFTITVYAIGTGTLGQH----- 229
            |:  |.|...||::.:|....:..||.|||::....::  .|..|.|:||.:    |.:|
 Frog   141 HQRRHHREFRFDIAKIPEGEAVTAAEFRIYKDYIRERF--ENETFQISVYQV----LQEHQGRDS 199

  Fly   230 TMEPLSSVNTTGDYVGWLELNVTEGLHEWLVKSKDNHGIYIGAHAVNRPDREVKLDDIGLIHRKV 294
            .:..|.|........|||..::|...:.|:|..:.|.|:.:...:::......|:  .|||....
 Frog   200 DLYELDSRTIWAAEEGWLVFDITTTSNHWVVNPQHNLGLQLSVESIDGQSINPKM--AGLIGTNG 262

  Fly   295 DDEFQPFMIGFFRGPEL----IKATA--HSSHHRSKRSASHPRKRKKSVSPNNVPLLEPMESTRS 353
            ....||||:.||:..|:    |::..  |.:.:|||...|....|..:::.|:     ..:..::
 Frog   263 PHNKQPFMVAFFKATEIHLRSIRSAGGKHRNQNRSKAPKSQEALRVSNIAENS-----STDQKQA 322

  Fly   354 CQMQTLYIDFKDLGWHDWIIAPEGYGAFYCSGECNFPLNAHMNATNHAIVQTLVHLLEPKKVPKP 418
            |:...||:.||||||.|||||||||.||||.|||.||||::||||||||||||||.:.|..||||
 Frog   323 CKKHELYVSFKDLGWQDWIIAPEGYAAFYCEGECAFPLNSYMNATNHAIVQTLVHFINPDTVPKP 387

  Fly   419 CCAPTRLGALPVLYHLNDENVNLKKYRNMIVKSCGCH 455
            |||||:|..:.|||..:..||.|||||||:|::||||
 Frog   388 CCAPTQLNPISVLYFDDSSNVILKKYRNMVVRACGCH 424

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
gbb	NP_477340.1	TGFb_propeptide	45..305	CDD:459906	69/267 (26%)
		TGF_beta_BMP5_like	353..455	CDD:381639	69/101 (68%)
bmp7	NP_989197.1	TGFb_propeptide	31..273	CDD:459906	69/267 (26%)
		TGF_beta_BMP7	318..424	CDD:381667	69/105 (66%)