Protein Alignment gbb and nodal3.1

DIOPT Version :9

• Sequence 1: NP_001286786.1
• Gene: gbb / 37778
• FlyBaseID: FBgn0024234
• Length: 455
• Species: Drosophila melanogaster
• Sequence 2: NP_988864.1
• Gene: nodal3.1 / 394458
• XenbaseID: XB-GENE-5964399
• Length: 401
• Species: Xenopus tropicalis
• Alignment Length: 508
• Identity: 107/508 - (21%)
• Similarity: 190/508 - (37%)
• Gaps: 185/508 - (36%)

  Fly    16 SLGLGMVLLMFVATTPPAVEATQS--------GIYIDNGKDQTIMHRVLSEDDKLDVSYEILEFL 72
            ||.|.:|....:...|||::..::        |...|||                     ..:|.
 Frog     5 SLFLCLVFSSPLMAMPPALQGRKAISPASILKGPSTDNG---------------------ARDFH 48

  Fly    73 GIAERPTHLSSHQLSLRKSAPKFLLDVYHRITAEEGLSDQDEDDDYERGHRSRRSADLEEDEGEQ 137
            |                :..|.|::.:|..|.                   |||..||
 Frog    49 G----------------RKFPHFMMQLYQNII-------------------SRRDKDL------- 71

  Fly   138 QKNFITDLDKRAIDESDIIMTFLNKRHHNVDELRHEHGRRLWFDVSNVPNDNYLVMAELRIYQNA 202
                 ::|:...:.|||.:.:|:.|.:..|.    .|. .|:||:|::..:|.|.:|||||.. .
 Frog    72 -----SNLEHPTLQESDTVQSFIAKSYTTVG----NHW-TLFFDMSSISTNNELKLAELRICL-P 125

  Fly   203 NEGKWLTANREFTITVYAIGTGTLGQHTMEPLSSVNTTGDYVGWLE-------------LNVTEG 254
            :.||    :...|:.:|         ||.:....:     ::|..:             .|:|..
 Frog   126 SFGK----SHSVTVEIY---------HTKDTKEKL-----FMGSFKTKISSALDADCKVFNLTMV 172

  Fly   255 LHEWLVKSKDNHGIYIGAHAVNRPDREVKLDDI---GLIHRKVDDEFQPFMIGFFRGPELIKATA 316
            ||.:|::.|                |.:|.:.|   ||:.|.::.....      :|.|.:....
 Frog   173 LHNYLIRGK----------------RLIKDEYIQAKGLLLRDLEKSAAE------KGAENVDTLK 215

  Fly   317 HSSHHRS--------------KRSASHP-----------------------------RKRKKSVS 338
            ...||.|              :||.:.|                             |:.||..:
 Frog   216 QDKHHVSDFAAERIILVVFAKERSQAKPDPPSLGKQLFPLKYGMADNANKVNGFRRLRRNKKEKT 280

  Fly   339 PNNVPLL--EPMESTR-SCQMQTLYIDFKDLGWHDWIIAPEGYGAFYCSGECNFPLNAHMNATNH 400
            ..:|...  :|:|..: .|:...:::||:.:||..||:.|:.|.|:.|...|..|||...:|||:
 Frog   281 RMDVGTTPPKPVEEIKPKCRKVDMFVDFQKIGWGSWIVYPKAYNAYRCESACAVPLNETDDATNY 345

  Fly   401 AIVQTLVHLLEPKKVPKPCCAPTRLGALPVLYHLNDENVNLKKYRNMIVKSCG 453
            :.:::|:.|.:.::...|.|.|.::.::.:||:.|:|.: |:.:..|||:.||
 Frog   346 SYIKSLLPLSDTERRECPSCVPVKMRSMSMLYYENEEFI-LRHHEEMIVEECG 397

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
gbb	NP_001286786.1	TGFb_propeptide	44..305	CDD:279078	52/276 (19%)
		TGFB	354..455	CDD:214556	33/100 (33%)
nodal3.1	NP_988864.1	TGFb_propeptide	53..>139	CDD:279078	32/135 (24%)
		TGFB	299..397	CDD:214556	31/98 (32%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	1	0.910