Protein Alignment gbb and tgfb3

DIOPT Version :9

• Sequence 1: NP_001286786.1
• Gene: gbb / 37778
• FlyBaseID: FBgn0024234
• Length: 455
• Species: Drosophila melanogaster
• Sequence 2: NP_919367.2
• Gene: tgfb3 / 369195
• ZFINID: ZDB-GENE-030723-4
• Length: 410
• Species: Danio rerio
• Alignment Length: 486
• Identity: 113/486 - (23%)
• Similarity: 186/486 - (38%)
• Gaps: 127/486 - (26%)

  Fly    17 LGLGMVLLMFVATTPPAVE-ATQSGIYIDNGKDQTIMHRVLSEDDKLDVSYEILEFLGIAERPTH 80
            ||.|::.::.:.:...::. :|.:.:.|||.|.:.:.          .:..:||..|.:...|..
Zfish     3 LGKGLLFVLLLNSVTMSLSLSTCTTVDIDNIKKKRVE----------AIRGQILSKLRLTSPPQT 57

  Fly    81 LSSHQ-----LSLRKSAPKFLLDVYHRITAEEGLSDQDEDDDYERG-HRSRRSADLEEDEGEQQK 139
            |...|     |:|..|. :.|||.:.:...:....|..|.:.|.:. |:      ....:|..:.
Zfish    58 LGPSQVPYQVLALYNST-RDLLDGFGKDRHQSCGQDNTETEYYAKEIHK------FNMIQGSPEN 115

  Fly   140 NFITDLDKRAIDESDIIMTFLNKRHHNVDELRHEHGRRLWFDVSNV-PNDNYLVMAELRIYQNAN 203
            |.:....|...                        .:...||||.: .|.:.|..||.|..:..|
Zfish   116 NDLPYCPKGIT------------------------SKVFRFDVSIMEKNASNLFRAEFRALRMPN 156

  Fly   204 EGKWLTANREFTITVYAIGTGTLGQHTMEPLSSVNTTGDYVG-----------WLELNVTEGLHE 257
            ..   |:..|..|.:|.|         :.|...:... .|:|           |:..:|||.:.|
Zfish   157 LS---TSRTEQRIELYQI---------LRPDEHIGKQ-RYIGRKNVMIGGTDEWVSFDVTETVRE 208

  Fly   258 WLVKSKDNHGIYIGAHA---VNRPDREV---------------KLDDIGLIH------RKVDDEF 298
            ||.....|.|:.|..|.   ..||:.|:               .::|.|.|.      :|..::.
Zfish   209 WLTNRATNLGLEISVHCPCHTFRPNGEIIENVNEALEVKFRGMDVEDDGPIRSDMGRLKKPKEQN 273

  Fly   299 QPFMIGFFRGPELIKATAHSSHHRSKRSASHPRKRKKSVSP----NNVPLLEPMESTRSCQMQTL 359
            .|.:|.....|..:.....|            |:||:::..    :|.        ..:|.::.|
Zfish   274 LPHLILMMLPPHRLDVLPTS------------RRRKRALDTKYCFSNY--------EENCCVRKL 318

  Fly   360 YIDFK-DLGWHDWIIAPEGYGAFYCSGECNFPLNAHMNATNHAIVQTLVHLLEPKKVPKPCCAPT 423
            ||||: ||||. ||..|:||.|.:|||.|.:..:|.   |.|:.:.:|.:.|.|:....|||.|.
Zfish   319 YIDFRQDLGWR-WIHEPKGYHANFCSGPCPYLRSAD---TTHSSLLSLYNTLNPEASASPCCVPQ 379

  Fly   424 RLGALPVLYHLNDENVNLKKYRNMIVKSCGC 454
            .|..|.:||::. ....:::..|||||||.|
Zfish   380 DLEPLTILYYVG-RTPKVEQLSNMIVKSCKC 409

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
gbb	NP_001286786.1	TGFb_propeptide	44..305	CDD:279078	60/302 (20%)
		TGFB	354..455	CDD:214556	42/102 (41%)
tgfb3	NP_919367.2	TGFb_propeptide	22..228	CDD:279078	53/259 (20%)
		TGF_beta	311..409	CDD:278448	41/102 (40%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_KOG3900
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	1	1.000	-	-
TreeFam	0	0.000	Not matched by this tool.
ZFIN	0	0.000	Not matched by this tool.
	3	2.810