Protein Alignment gbb and tgfb1a

DIOPT Version :9

• Sequence 1: NP_001286786.1
• Gene: gbb / 37778
• FlyBaseID: FBgn0024234
• Length: 455
• Species: Drosophila melanogaster
• Sequence 2: NP_878293.1
• Gene: tgfb1a / 359834
• ZFINID: ZDB-GENE-030618-1
• Length: 377
• Species: Danio rerio
• Alignment Length: 417
• Identity: 102/417 - (24%)
• Similarity: 170/417 - (40%)
• Gaps: 111/417 - (26%)

  Fly    67 EILEFLGIAERPTHLSSHQLSLRKSAPKFLLDVYHRITAEEGLSD---------QDEDDDYERGH 122
            :||..|.:|:.|...:...   .:..|..||.:|:. |.|  ||:         ||||:||
Zfish    42 QILSKLRMAKEPESGADDD---GQKIPDSLLSLYNS-TVE--LSEEMKTKIVPVQDEDEDY---- 96

  Fly   123 RSRRSADLEEDEGEQQKNFITDLDKRAIDESDIIMTFLNKRHH---NVDELRHEHGRRLWFDVSN 184
                       .|::...|:....:.            |.:|.   ||.|::.           :
Zfish    97 -----------FGKEVHKFVFQQAQN------------NTKHQMFFNVSEMKR-----------S 127

  Fly   185 VPNDNYLVMAELRI-YQNANEGKWLTANREFTITVYAIGTGTLGQHTMEPLSSVNTTGDYVGWLE 248
            :|:...|..||||: .:|.      |.::|..:.:|. |.|...::......|.:.:.   .||.
Zfish   128 IPDYRLLSQAELRLRIKNP------TMDQEQRLELYR-GVGDQARYLGTRFVSKDLSN---RWLS 182

  Fly   249 LNVTEGLHEWLVKSKDNHGIYIGAH---------------AVNRPDREVKLDDIGLIHRKVDDEF 298
            .:|.:.:.|||..|:|...:.:..:               .::..|:: :.|..||    .|...
Zfish   183 FDVKQTMIEWLQGSEDEETLELRLYCDCKANQQSTDKFLFTISGLDKQ-RGDTAGL----ADMMV 242

  Fly   299 QPFMIGFFRGPELIKATAHSSHHRSKRSASHPRKRKKSVSPNNVPLLEPMESTRSCQMQTLYIDF 363
            :|:::          |.:..|:..|..|.   |||:...:.....     |.|.:|.|:.|||||
Zfish   243 KPYIL----------ALSLPSNGNSLASV---RKRRAVGTDETCD-----EKTETCCMRKLYIDF 289

  Fly   364 -KDLGWHDWIIAPEGYGAFYCSGECNFPLNAHMNATNHAIVQTLVHLLEPKKVPKPCCAPTRLGA 427
             ||||| .||..|:||.|.||.|.|.:..||.   ..::.:..|.....|....:|||.|..|..
Zfish   290 RKDLGW-KWIHKPKGYFANYCMGSCTYIWNAE---NKYSQILALYKHHNPGASAQPCCVPAILDP 350

  Fly   428 LPVLYHLNDENVNLKKYRNMIVKSCGC 454
            ||:||::..:: .:::..||:|::|.|
Zfish   351 LPILYYVGRQH-KVEQLSNMVVRNCKC 376

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
gbb	NP_001286786.1	TGFb_propeptide	44..305	CDD:279078	53/265 (20%)
		TGFB	354..455	CDD:214556	40/102 (39%)
tgfb1a	NP_878293.1	TGFb_propeptide	20..248	CDD:366248	53/274 (19%)
		TGF_beta_TGFB1	280..377	CDD:381654	40/102 (39%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_KOG3900
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
ZFIN	0	0.000	Not matched by this tool.
	2	1.810