Protein Alignment gbb and dpp

DIOPT Version :9

• Sequence 1: NP_001286786.1
• Gene: gbb / 37778
• FlyBaseID: FBgn0024234
• Length: 455
• Species: Drosophila melanogaster
• Sequence 2: NP_477311.1
• Gene: dpp / 33432
• FlyBaseID: FBgn0000490
• Length: 588
• Species: Drosophila melanogaster
• Alignment Length: 462
• Identity: 132/462 - (28%)
• Similarity: 198/462 - (42%)
• Gaps: 115/462 - (24%)

  Fly    75 AERPTHLSSHQLSLRKSAPKFLLD----------VYHRITAEEG---------LSDQDEDD---- 116
            |...:|.||...|:....|..:||          ....|.||:|         :.|:.:.|
  Fly   159 ASTESHQSSSIESIFVEEPTLVLDREVASINVPANAKAIIAEQGPSTYSKEALIKDKLKPDPSTL 223

  Fly   117 -DYERGHRS----RRSADLEEDE---GEQQKNFITDLDKRAIDESDI------------IMTFLN 161
             :.|:...|    :|...::..:   .|..|....::....:|..:|            :.:|.:
  Fly   224 VEIEKSLLSLFNMKRPPKIDRSKIIIPEPMKKLYAEIMGHELDSVNIPKPGLLTKSANTVRSFTH 288

  Fly   162 KRHHNVDELRHEHGRRLWFDVSNVPNDNYLVMAELRIYQNANEGKWL----TANR-EFTITVYAI 221
            |.....|...|.|..||.|||.::|.|..|..|||::.::|...:.:    :||| .:.:.||.|
  Fly   289 KDSKIDDRFPHHHRFRLHFDVKSIPADEKLKAAELQLTRDALSQQVVASRSSANRTRYQVLVYDI 353

  Fly   222 -GTGTLGQHTMEP-----------LSSVNTTGDYVGWLELNVTEGLHEWLVKSKDNHGIYIGAHA 274
             ..|..||.  ||           |:|.:|       :.|:|...:..||...:.|:|:.:....
  Fly   354 TRVGVRGQR--EPSYLLLDTKTVRLNSTDT-------VSLDVQPAVDRWLASPQRNYGLLVEVRT 409

  Fly   275 VN----RPDREVKLDDIGLIHRKVDDEFQPFMIGFFRGPELIKATAHSSHH-------------- 321
            |.    .|...|:|      .|..|:..:.:.   .:.|.|...|....|.
  Fly   410 VRSLKPAPHHHVRL------RRSADEAHERWQ---HKQPLLFTYTDDGRHKARSIRDVSGGEGGG 465

  Fly   322 ---RSKRSASHPRKRKKSVSPNNVPLLEPMESTRSCQMQTLYIDFKDLGWHDWIIAPEGYGAFYC 383
               |:||....|.:||              ....:|:..:||:||.|:||.|||:||.||.|:||
  Fly   466 KGGRNKRQPRRPTRRK--------------NHDDTCRRHSLYVDFSDVGWDDWIVAPLGYDAYYC 516

  Fly   384 SGECNFPLNAHMNATNHAIVQTLVHLLEPKKVPKPCCAPTRLGALPVLYHLNDEN-VNLKKYRNM 447
            .|:|.|||..|.|:||||:|||||:.:.|.||||.||.||:|.::.:|| |||:: |.||.|:.|
  Fly   517 HGKCPFPLADHFNSTNHAVVQTLVNNMNPGKVPKACCVPTQLDSVAMLY-LNDQSTVVLKNYQEM 580

  Fly   448 IVKSCGC 454
            .|..|||
  Fly   581 TVVGCGC 587

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
gbb	NP_001286786.1	TGFb_propeptide	44..305	CDD:279078	64/293 (22%)
		TGFB	354..455	CDD:214556	58/102 (57%)
dpp	NP_477311.1	TGFb_propeptide	225..444	CDD:279078	52/236 (22%)
		TGFB	487..588	CDD:214556	58/102 (57%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	1	0.930	-	-		C45466524
Domainoid	1	1.000	126	1.000	Domainoid score	I3358
eggNOG	1	0.900	-	-		E1_KOG3900
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	1	1.010	-	-		D1063560at2759
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	1	1.000	-	-		otm14749
orthoMCL	0	0.000	Not matched by this tool.
Panther	1	1.100	-	-	P	PTHR11848
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	1	1.000	-	-		X157
	8	7.850