Protein Alignment gbb and Lefty2

DIOPT Version :9

• Sequence 1: NP_001286786.1
• Gene: gbb / 37778
• FlyBaseID: FBgn0024234
• Length: 455
• Species: Drosophila melanogaster
• Sequence 2: NP_796073.1
• Gene: Lefty2 / 320202
• MGIID: 2443573
• Length: 368
• Species: Mus musculus
• Alignment Length: 388
• Identity: 79/388 - (20%)
• Similarity: 129/388 - (33%)
• Gaps: 137/388 - (35%)

  Fly   127 SADLEE--DEGEQQKNFITDLDKRAIDESDIIMTFLNKRHHNVDELRHEHGRRLWFDVS------ 183
            |||:||  .....:..::..|.....|.|      ..||..  ...|...||.|..:.|
Mouse    45 SADVEEMAIPTHVRSQYVALLQGSHADRS------RGKRFS--QNFREVAGRFLMSETSTHLLVF 101

  Fly   184 ----NVPNDNYLVMAELRIYQNANEGKWLTANREF----------TITVYAIGTGTLGQHTMEPL 234
                .:|.::.||.|.||::|   |....||.|.|          .:|:..:.....|.:....:
Mouse   102 GMEQRLPPNSELVQAVLRLFQ---EPVPRTALRRFERLSPHSARARVTIEWLRVREDGSNRTALI 163

  Fly   235 SSVNTTGDYVGWLELNVTEGLHEWLVKSKDNHGIYIGAHAVNRPDREVKLDDIGLIHRKVDDEFQ 299
            .|...:....||...:|||.::.|              ..::||
Mouse   164 DSRLVSIHESGWKAFDVTEAVNFW--------------QQLSRP--------------------- 193

  Fly   300 PFMIGFFRGPELIKATAHSSH--------HRSKRSAS----------------HPRKRKKSVSPN 340
                   |.|.|::.:....|        |:..|.|:                |....|...:..
Mouse   194 -------RQPLLLQVSVQREHLGPGTWSAHKLVRFAAQGTPDGKGQGEPQLELHTLDLKDYGAQG 251

  Fly   341 NV-PLLEPMESTRSCQMQTLYIDFKDLGW-HDWIIAPEGYGAFYCSGECNFPLNAHMNATNHAIV 403
            |. |.:...|.||.|: |.:|:|.:.:.| .:||:.|.|:..:.|.|.|
Mouse   252 NCDPEVPVTEGTRCCR-QEMYLDLQGMKWAENWILEPPGFLTYECVGSC---------------- 299

  Fly   404 QTLVHLLE------PKKVPKPCCAPTRLGALPVLYHLND------ENVNLKKYRNMIVKSCGC 454
               :.|.|      |...|:.|.| :.:.:||::..:.:      :.|:|.   ||.|::|.|
Mouse   300 ---LQLPESLTIGWPFLGPRQCVA-SEMTSLPMIVSVKEGGRTRPQVVSLP---NMRVQTCSC 355

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
gbb	NP_001286786.1	TGFb_propeptide	44..305	CDD:279078	38/199 (19%)
		TGFB	354..455	CDD:214556	27/114 (24%)
Lefty2	NP_796073.1	TGFb_propeptide	<106..211	CDD:279078	27/149 (18%)
		TGF_beta	263..355	CDD:278448	28/115 (24%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_KOG3900
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	2	1.810