Protein Alignment gbb and Bmp5

DIOPT Version :10

• Sequence 1: NP_477340.1
• Gene: gbb / 37778
• FlyBaseID: FBgn0024234
• Length: 455
• Species: Drosophila melanogaster
• Sequence 2: NP_001101638.1
• Gene: Bmp5 / 315824
• RGDID: 1305979
• Length: 454
• Species: Rattus norvegicus
• Alignment Length: 459
• Identity: 155/459 - (33%)
• Similarity: 234/459 - (50%)
• Gaps: 82/459 - (17%)

  Fly    44 DNGKDQTIMHRVLSEDDKLDVSYEILEFLGIAERPTHLSSHQLSLRKSAPKFLLDVYHRITAEEG 108
            ||....:.::|.|...::.::..|||..||:..||...|..:.:  .|||.|:||:|:.:.:||.
  Rat    31 DNHVHSSFIYRRLRNHERREIQREILSILGLPHRPRPFSPGKQA--SSAPLFMLDLYNAMASEEN 93

  Fly   109 LSDQD---------EDDDYERG---------HR------------SRRSADLEEDEGEQQKNFIT 143
            ..:.:         |..:..:|         ||            |...|.|.:      .||:.
  Rat    94 PEESEYLVRVSLAGEAKETRKGYPASPNGYAHRLHLPPRIPLTTQSPPLASLHD------TNFLN 152

  Fly   144 DLDKRAIDESDIIMTFLNKRHHNVDELRHE--HGRRLWFDVSNVPNDNYLVMAELRIYQNANEGK 206
            |        :|::|:|:|....:.| ..|:  |.:...||::.:|:...:..||.|||::.:..:
  Rat   153 D--------ADMVMSFVNLVERDKD-FSHQRRHYKEFRFDLTQIPHGEAVTAAEFRIYKDKSNHR 208

  Fly   207 WLTANREFTITVYAIGTGTLGQHTMEPLSSVNTTGDY------------VGWLELNVTEGLHEWL 259
            :  .|....|::|.|    :.::|       |...|.            ||||..::|...:.|:
  Rat   209 F--ENETIKISIYQI----IKEYT-------NRDADLFLLDTRKAQALDVGWLVFDITVTSNHWV 260

  Fly   260 VKSKDNHGIYIGAHAVNRPDREVKLDDIGLIHRKVDDEFQPFMIGFFRGPELIKATAHSSHHRSK 324
            :..::|.|:.:.|...:  .|.:.:...||:.|......||||:.||:..|::..:..::   ||
  Rat   261 INPQNNLGLQLCAETGD--GRSINVKSAGLVGRHGPQSKQPFMVAFFKASEVLLRSVRAA---SK 320

  Fly   325 RSASHPRKRKKSVSPNNVPL---LEPMESTRSCQMQTLYIDFKDLGWHDWIIAPEGYGAFYCSGE 386
            |...:..|......|:.:|.   ....|..::|:...||:.|:||||.|||||||||.||||.||
  Rat   321 RKNQNRNKSSSHQDPSRIPSAGDYNTSEQKQACKKHELYVSFRDLGWQDWIIAPEGYAAFYCDGE 385

  Fly   387 CNFPLNAHMNATNHAIVQTLVHLLEPKKVPKPCCAPTRLGALPVLYHLNDENVNLKKYRNMIVKS 451
            |:|||||||||||||||||||||:.|..|||||||||:|.|:.|||..:..||.|||||||:|:|
  Rat   386 CSFPLNAHMNATNHAIVQTLVHLMFPDHVPKPCCAPTKLNAISVLYFDDSSNVILKKYRNMVVRS 450

  Fly   452 CGCH 455
            ||||
  Rat   451 CGCH 454

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
gbb	NP_477340.1	TGFb_propeptide	45..305	CDD:459906	69/303 (23%)
		TGF_beta_BMP5_like	353..455	CDD:381639	73/101 (72%)
Bmp5	NP_001101638.1	TGFb_propeptide	32..304	CDD:459906	69/303 (23%)
		TGF_beta_BMP5	342..454	CDD:381665	74/111 (67%)