Protein Alignment gbb and lft2

DIOPT Version :9

• Sequence 1: NP_001286786.1
• Gene: gbb / 37778
• FlyBaseID: FBgn0024234
• Length: 455
• Species: Drosophila melanogaster
• Sequence 2: NP_571036.1
• Gene: lft2 / 30146
• ZFINID: ZDB-GENE-990630-11
• Length: 362
• Species: Danio rerio
• Alignment Length: 478
• Identity: 94/478 - (19%)
• Similarity: 161/478 - (33%)
• Gaps: 166/478 - (34%)

  Fly    19 LGMVLLMFVATTPPAVEATQSGIYIDNGKDQTIMHRVLSEDDKLDVSYEILEFLGIAER------ 77
            :.:.:.:|:.||  |:..||.           ..|.        |:...:|:.||:.|.
Zfish     1 MALFIQLFILTT--AISLTQG-----------FQHE--------DIKQALLQKLGLTEPPRIQKR 44

  Fly    78 -------PTHLSSHQLSLRKSAPKFLLDVYHRITAEEGLSDQDEDDDYERGHRSRRSADLEEDEG 135
                   |.|:.|..||:.|.                              |..||...|....|
Zfish    45 DLENLVVPAHIKSKYLSMLKL------------------------------HHQRRRRSLPSLAG 79

  Fly   136 EQQKNFITDLDKRAIDESDIIMTFLNKRHHNVD---ELRHEH--GRRLWFDV-SNVPNDNYLVMA 194
                                   .|...|.|.|   |:::..  .:||.||: :.:..:..:.||
Zfish    80 -----------------------ILRGIHGNADITGEIKYSDTTRQRLVFDMEARLQENTEVTMA 121

  Fly   195 ELRIYQNANEGKWLTANREF------TITVYAIGTGTLGQHTMEPLSSVNTTGDYVGWLELNVTE 253
            ||:::|.|.:.......|..      .:::|.:.....|.:....|.|........||...:||:
Zfish   122 ELKLFQTAAQSPSKPERRHHRPINHARVSIYWVEVLENGSNRTSLLDSRLVPIHESGWRSFDVTQ 186

  Fly   254 GLHEWLVKSKDNHGIYI---------GAHAVNRPDREVKLDDIGLIHRKVDDEFQPFMIGFFRGP 309
            .:|.| .||:....:::         |::|.....|         :.....|..:..:......|
Zfish   187 AIHYW-SKSQKKAPLHLEVWTEGERPGSYAAEMAKR---------VRFATQDPKENTLEKDMGAP 241

  Fly   310 ELIKATAHSSHHRSKRSASHPRKRKKSVSPNNVPLLEPMESTRSCQMQTLYIDFKDLGWHD-WII 373
            ||:..|.....:.|:.:.:.        |||         |::.|: :..:|:|::|.|.. |||
Zfish   242 ELVLYTLDLDEYGSQGNCNS--------SPN---------SSKCCR-EEHFINFRELTWTQYWII 288

  Fly   374 APEGYGAFYCSGECNFPLNAHMNATNHAIVQTLVHLLEPKK----VPKPCCAPTRLGALPVLYHL 434
            .|.||.||.|:|.|.                      :||:    ..:..||......||::|.:
Zfish   289 EPAGYQAFRCAGGCK----------------------QPKRGFYGYGQRTCAVMESAPLPMMYLV 331

  Fly   435 ND---ENVNLKKYRNMIVKSCGC 454
            ..   ..:.:.::.||||:.|||
Zfish   332 KKGDYTEIEVAEFPNMIVEKCGC 354

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
gbb	NP_001286786.1	TGFb_propeptide	44..305	CDD:279078	49/294 (17%)
		TGFB	354..455	CDD:214556	30/109 (28%)
lft2	NP_571036.1	TGFb_propeptide	15..204	CDD:366248	47/261 (18%)
		TGF_beta_LEFTY1_2	267..354	CDD:381636	28/109 (26%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_KOG3900
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
ZFIN	0	0.000	Not matched by this tool.
	2	1.810