Protein Alignment gbb and gdf3

DIOPT Version :9

• Sequence 1: NP_001286786.1
• Gene: gbb / 37778
• FlyBaseID: FBgn0024234
• Length: 455
• Species: Drosophila melanogaster
• Sequence 2: NP_571023.1
• Gene: gdf3 / 30125
• ZFINID: ZDB-GENE-980526-389
• Length: 355
• Species: Danio rerio
• Alignment Length: 418
• Identity: 119/418 - (28%)
• Similarity: 185/418 - (44%)
• Gaps: 102/418 - (24%)

  Fly    57 SEDDKLDVSYEILEFLGIAERPTHLSSHQLSLRKSAPKFLLDVYHRITAEEGLSDQDEDDDY-ER 120
            :|||.|......|..:|:..||.  .||..::    |..:..::.: .:::.::|.....:| .|
Zfish    19 AEDDGLVQEKLFLSSMGLWSRPK--PSHHAAV----PSQMWKIFKQ-ASKQTVNDPCVVSEYGVR 76

  Fly   121 GHRSRRSADLEEDEGEQQKNFITDLDKRAIDESDIIMTFLNKRHHNVDELRHEHGRRLWFDVSNV 185
            |:..|    ..:|:|             ::..:..:.:|...|.|            |:|::|.:
Zfish    77 GNIVR----FMQDQG-------------SLISAPAVHSFNCVRKH------------LFFNMSVL 112

  Fly   186 PNDNYLVMAELRIYQNANEGKWLTANREFTITVYAIGTGTLGQHTMEP-----LSSVNTTGDYVG 245
            .....|.:|:|.:  ...:...|.....|::.:|.:...||...|.|.     .|...:.|.:..
Zfish   113 EEVEQLSLAQLEM--KFKQDLLLLGPHVFSVDLYRVLKTTLKGVTHESSRKLLQSQTLSPGAHAS 175

  Fly   246 WLELNVTEGLHEWLVKSKDNHGIYIGA-----------HA-VNRPDREVKLDDIGLIHRKVDDEF 298
            .| :|:|.....|. |.:.|.|:.:..           || |..||          ||..:
Zfish   176 VL-VNLTNLAQSWR-KPEKNFGMQLELQVMHLNNMLHDHAYVQIPD----------IHATL---- 224

  Fly   299 QPFMIGFFRGPELIKATAHSSHHRSKRSASH--PRKRKKSVSPNNVPLLEPMESTRSCQMQTLYI 361
                       .::.........|.|||||:  |      |:|:||           |:.:.|||
Zfish   225 -----------VVVSLNPLQCRSRRKRSASYYLP------VTPSNV-----------CKPRRLYI 261

  Fly   362 DFKDLGWHDWIIAPEGYGAFYCSGECNFPLNAHMNATNHAIVQTLVHLLEPKKVPKPCCAPTRLG 426
            ||||:||.||||||:||.|.||.|||.|||:..:|.|||||:|||||..:||..|:|||.|.:|.
Zfish   262 DFKDVGWQDWIIAPQGYLANYCHGECPFPLSESLNGTNHAILQTLVHSFDPKGTPQPCCVPIKLS 326

  Fly   427 ALPVLYHLNDENVNLKKYRNMIVKSCGC 454
            .:.:||:.|::||.|:.|.:|:|..|||
Zfish   327 PISMLYYDNNDNVVLRHYEDMVVDECGC 354

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
gbb	NP_001286786.1	TGFb_propeptide	44..305	CDD:279078	50/265 (19%)
		TGFB	354..455	CDD:214556	58/101 (57%)
gdf3	NP_571023.1	TGFb_propeptide	27..200	CDD:279078	39/212 (18%)
		TGFB	254..355	CDD:214556	58/101 (57%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_KOG3900
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
ZFIN	0	0.000	Not matched by this tool.
	2	1.810