DRSC/TRiP Functional Genomics Resources

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Protein Alignment gbb and Gdf15

DIOPT Version :9

Sequence 1:NP_001286786.1 Gene:gbb / 37778 FlyBaseID:FBgn0024234 Length:455 Species:Drosophila melanogaster
Sequence 2:NP_062089.1 Gene:Gdf15 / 29455 RGDID:2674 Length:303 Species:Rattus norvegicus


Alignment Length:138 Identity:44/138 - (31%)
Similarity:71/138 - (51%) Gaps:17/138 - (12%)


- Green bases have known domain annotations that are detailed below.


  Fly   318 SSHHRSKRSAS-HPRKRKKSVSPNNVPLLEPMESTRSCQMQTLYIDFKDLGWHDWIIAPEGYGAF 381
            |:..|.:|||. |||...            |:...|.|.::|:....:||||.||:::|......
  Rat   181 SAAGRGRRSAHLHPRDSC------------PLGPGRCCHLETVQATLEDLGWSDWVLSPRQLQLS 233

  Fly   382 YCSGECNFPLNAHMNATNHAIVQTLVHLLEPKKVPKPCCAPTRLGALPVLYHLNDENVNLKKYRN 446
            .|.|||.   :.:.:|..||:::..:|.|:|.:||.|||.|:....: ||.|..|..|:|:.|.:
  Rat   234 MCVGECP---HLYRSANTHALIKARLHGLQPDRVPAPCCVPSSYTPV-VLMHRTDSGVSLQTYDD 294

  Fly   447 MIVKSCGC 454
            ::.:.|.|
  Rat   295 LVAQGCHC 302

Known Domains:


Indicated by green bases in alignment.

GeneSequenceDomainRegion External IDIdentity
gbbNP_001286786.1 TGFb_propeptide 44..305 CDD:279078
TGFB 354..455 CDD:214556 34/101 (34%)
Gdf15NP_062089.1 TGF_beta 204..302 CDD:278448 34/101 (34%)
Blue background indicates that the domain is not in the aligned region.


Information from Original Tools:


Tool Simple Score Weighted Score Original Tool Information
BLAST Result Score Score Type Cluster ID
Compara 00.000 Not matched by this tool.
Domainoid 00.000 Not matched by this tool.
eggNOG 1 0.900 - - E1_KOG3900
Hieranoid 00.000 Not matched by this tool.
Homologene 00.000 Not matched by this tool.
Inparanoid 00.000 Not matched by this tool.
OMA 00.000 Not matched by this tool.
OrthoDB 00.000 Not matched by this tool.
OrthoFinder 00.000 Not matched by this tool.
OrthoInspector 00.000 Not matched by this tool.
orthoMCL 00.000 Not matched by this tool.
Panther 00.000 Not matched by this tool.
Phylome 1 0.910 - -
SonicParanoid 00.000 Not matched by this tool.
SwiftOrtho 1 1.000 - -
TreeFam 00.000 Not matched by this tool.
32.810

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