Protein Alignment gbb and Bmp2

DIOPT Version :9

• Sequence 1: NP_001286786.1
• Gene: gbb / 37778
• FlyBaseID: FBgn0024234
• Length: 455
• Species: Drosophila melanogaster
• Sequence 2: NP_058874.2
• Gene: Bmp2 / 29373
• RGDID: 2211
• Length: 394
• Species: Rattus norvegicus
• Alignment Length: 429
• Identity: 133/429 - (31%)
• Similarity: 198/429 - (46%)
• Gaps: 111/429 - (25%)

  Fly    57 SEDDKLDVSYEILEFLGIAERPTHLSSHQLSLRKSAPKFLLDVYHRITAEEGLSDQDEDDDYERG 121
            |:|...:....:|...|:.:|||.      |.....|.::||:|.|.:.:.|....|
  Rat    45 SDDVLSEFELRLLSMFGLKQRPTP------SKDVVVPPYMLDLYRRHSGQPGAPAPD-------- 95

  Fly   122 HRSRRSADLEEDEGEQQKNFITDLDKRAIDESDIIMTFLNKRHHN--VDELRHEHG---RRLWFD 181
            ||..|:|                      ..::.:.:|    ||.  ::||....|   ||.:|:
  Rat    96 HRLERAA----------------------SRANTVRSF----HHEEAIEELPEMSGKTSRRFFFN 134

  Fly   182 VSNVPNDNYLVMAELRIYQNANEG-----------------KWLTANREFTITVYAIGTGTLGQH 229
            :|:||.|.:|..|||:|::...:.                 |..||:.:|.:| ..:.|..:.|:
  Rat   135 LSSVPTDEFLTSAELQIFREQMQEALGNSSFQHRINIYEIIKPATASSKFPVT-RLLDTRLVTQN 198

  Fly   230 TMEPLSSVNTTGDYVGWLELNVTEGLHEWLVKSKDNHGIYIG-AHAVNRP---DREVKLDDIGLI 290
            |.:             |...:||..:..|..:...|||..:. ||...:|   .|.|::.  ..:
  Rat   199 TSQ-------------WESFDVTPAVMRWTAQGHTNHGFVVEVAHLEEKPGVSKRHVRIS--RSL 248

  Fly   291 HRKVDD----EFQPFMIGFFRGPELIKATAHSSHHRSKRSASH-PRKRKKSVSPNNVPLLEPMES 350
            |:  |:    :.:|.::.|  |.:   ...|..|.|.||.|.| .|||.||
  Rat   249 HQ--DEHSWSQVRPLLVTF--GHD---GKGHPLHKREKRQAKHKQRKRLKS-------------- 292

  Fly   351 TRSCQMQTLYIDFKDLGWHDWIIAPEGYGAFYCSGECNFPLNAHMNATNHAIVQTLVHLLEPKKV 415
              ||:...||:||.|:||:|||:||.||.||||.|||.|||..|:|:||||||||||:.:. .|:
  Rat   293 --SCKRHPLYVDFSDVGWNDWIVAPPGYHAFYCHGECPFPLADHLNSTNHAIVQTLVNSVN-SKI 354

  Fly   416 PKPCCAPTRLGALPVLYHLNDENVNLKKYRNMIVKSCGC 454
            ||.||.||.|.|:.:||...:|.|.||.|::|:|:.|||
  Rat   355 PKACCVPTELSAISMLYLDENEKVVLKNYQDMVVEGCGC 393

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
gbb	NP_001286786.1	TGFb_propeptide	44..305	CDD:279078	60/277 (22%)
		TGFB	354..455	CDD:214556	58/101 (57%)
Bmp2	NP_058874.2	TGFb_propeptide	41..265	CDD:395559	60/277 (22%)
		Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite	269..291		10/21 (48%)
		TGF_beta_BMP2	292..394	CDD:381660	60/119 (50%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_KOG3900
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
SonicParanoid	1	1.000	-	-		X157
SwiftOrtho	1	1.000	-	-
TreeFam	0	0.000	Not matched by this tool.
	4	3.810